Saturday, June 15, 2024

Does Estrogen Cause Cancer To Grow

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You Have More Power Than You Have Been Told

Does Hormone Replacement Therapy Cause Breast Cancer? Estrogen Effects on Women!

You have more power over your risk of breast cancer than you think. There are many steps you can take to protect yourself. Each one of them has other positive domino effects for your hormonal balance and overall health:

1. Help with Estrogen Metabolism

If theres one trio of supplements I recommend for preventing breast cancer and promoting overall hormone health, its the combination of DIM, sulforaphane, and calcium d-glucarate. Heres a breakdown of these major estrogen metabolizers.

DIM: Also known as diindolylmethane, DIM is a compound generated when the body breaks down cruciferous vegetables such as broccoli, cabbage, and cauliflower. It is best known as a nutrient that supports healthy estrogen metabolism as well as the prevention of hormone-related cancers by its anti-estrogenic and anti-androgenic effects. It supports:

  • Phase 1 liver detoxification
  • The breakdown of estrogen into clean estrogens, not the antagonistic dirty ones
  • A healthy balance of testosterone and estrogen by acting as an aromatase inhibitor, blocking some testosterone from converting to estrogen
  • The cells from the damaging effects of oxidation

I personally use and recommend our DIM. The recommended dose is 100 mg to 200 mg per day.

I personally use and recommend our Brocco Power . The recommended dosage is 500 mg a day.

I personally use and recommend our Calcium-D-Glucarate. Recommended dosage of calcium d-glucarate ranges from 150 mg to 300 mg per day, taken with meals.

For Breast Protection:

Talcum Powder And Asbestos

Habitual use of talcum powder on the genital area may increase the risk for ovarian cancer, but the evidence is not strong. A study at Harvard Medical School found that using talc this way doubled the risk, but other studies found no increased risk. Some researchers believe that talc may be carcinogenic because it contains particles of asbestos, a known carcinogen. Its been shown that rates of ovarian cancer are higher than normal in women whose jobs expose them to asbestos.

What Is A Hormone Receptor

In breast cancer, hormone receptors are the proteins located in and around breast cells. These receptors signal cells both healthy and cancerous to grow. In the case of breast cancer, the hormone receptors tell the cancer cells to grow uncontrollably, and a tumor results.

Hormone receptors can interact with estrogen or progesterone. Estrogen receptors are the most common. This is why ER-positive is the most common form of breast cancer.

Some people are diagnosed with progesterone receptor-positive breast cancer. The key difference is whether cancerous cells are getting growth signals from estrogen or progesterone.

Testing for hormone receptors is important in treating breast cancer. In some cases, there are no hormone receptors present, so hormone therapy isnt a good treatment option. This is called hormone receptor-negative breast cancer.

According to BreastCancer.org, about 2 out of 3 people with breast cancer have some form of hormone receptors present. This makes them candidates for hormone therapy.

Read Also: What Doctor Checks Your Hormone Levels

How Estrogen Feeds Cancer

A high proportion of breast cancers are Estrogen Receptor Positive. This means they have a large number of estrogen receptors, indicating that estrogen is helping to feed their growth.

The American Cancer Society;explains Estrogen Receptor Positive cancer like this:

Breast cancer that involves estrogen and progesterone receptors is likely to respond to treatments known as endocrine therapies. In medicine, drugs such as Tamoxifen are used to block the estrogen receptors and help prevent the cancer from recurring. In post-menopausal women, drugs called aromatase inhibitors may be more beneficial to help stop production of estrogen.

But what women with breast cancer are rarely told? That as well as taking medication , they can adopt diet and lifestyle strategies which can effectively reduce high levels of the antagonistic estrogen, estradiol.

And addressing estrogen dominance through lifestyle is equally important if you dont have cancer. By reducing your estradiol levels you stabilize your progesterone levels too which in the long-term, could reduce your risk of breasts cancers that are ER Positive and PR Positive.

Reducing Estrogen Dominance is also important to reduce the risk of other ER Positive cancers of the:

  • Ovaries
  • Prostate, in men

What Is Intermittent Adt

Menopause Oestrogen Progesterone Cancer Cells Pre Uterus ...

Researchers have investigated whether a technique called intermittent androgen deprivation can delay the development of hormone resistance. With intermittent androgen deprivation, hormone therapy is given in cycles with breaks between drug administrations, rather than continuously. An additional potential benefit of this approach is that the temporary break from the side effects of hormone therapy may improve a mans quality of life.

Randomized clinical trials have shown similar overall survival with continuous ADT or intermittent ADT among men with metastatic or recurrent prostate cancer, with a reduction in some side effects for intermittent ADT .

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Too Much Estrogen Causes Disease

Hormone Imbalance Associated Diseases

Estrogen Dominance hormone imbalance is associated with many different diseases. Uterine Fibroids,Endometriosis, Adenomyosis, Fibrocystic Breast Disease , Migraine Headaches associatedwith the menstrual cycle, premenstrual syndrome, ovarian cysts, breast cancer, endometrial cancer, benign prostatic hypertrophy, restless leg syndrome, birth defects and prostate cancer are all associated with too much estrogen.Both natural, pharmaceutically modified, and chemical estrogen mimics are associated with thesediseases.

How Will I Know That My Hormone Therapy Is Working

Doctors cannot predict how long hormone therapy will be effective in suppressing the growth of any individual mans prostate cancer. Therefore, men who take hormone therapy for more than a few months are regularly tested to determine the level of PSA in their blood. An increase in PSA level may indicate that a mans cancer has started growing again. A PSA level that continues to increase while hormone therapy is successfully keeping androgen levels extremely low is an indicator that a mans prostate cancer has become resistant to the hormone therapy that is currently being used.;

Read Also: How Safe Is Bioidentical Hormone Replacement Therapy

Cannabis Oil As A Breast Cancer Treatment

QUESTION:

ANSWER:

“An in vitro study of the effect of CBD on programmed cell death in breast cancer cell lines found that CBD induced programmed cell death, independent of the CB1, CB2, or vanilloid receptors. CBD inhibited the survival of both estrogen receptorpositive and estrogen receptornegative breast cancer cell lines, inducing apoptosis in a concentration-dependent manner while having little effect on nontumorigenic mammary cells.Other studies have also shown the antitumor effect of cannabinoids in preclinical models of breast cancer.”

“CBD inhibited the survival of both estrogen receptorpositive and estrogen receptornegative breast cancer cell

Be Smart With Smartphones

Does Soy Cause Cancer?

Please, do NOT keep your cellphone in your bra. Cellphones may cause negative changes to tissues of our body. While there arent yet any studies on cell phones and breast disease, cancer expert, Robert Nagourney of the Nagourney Cancer Institute, shared a case of a young woman who regularly carried her cell phone in her bra and later developed multiple breast tumors in that exact spot. Of course, thats one person whose story was actually recorded, but its better to be safe than sorry.

Read Also: How To Tell If Your Hormones Are Off Balance

What Is Unique About The Young Mammary Gland That Makes It So Susceptible To Cancer Induction And Protection

The fact that two crucial reproductive events, menarche and young age at parity, have the greatest effect on lifetime breast cancer risk suggests that the young mammary gland represents a crucial window in tumorigenic susceptibility. Why this is the case is less clear. Based on the epidemiological evidence for this, a few hypotheses have been generated, but again few have been tested experimentally, and this work is largely restricted to rodent models.

Menopausal Hormone Therapy And Cancer Risk

For decades, women have used hormone therapy to ease symptoms of menopause, such as hot flashes and sweating. This is called;menopausal hormone therapy, and you may see it abbreviated as HT or MHT. You may also hear it described as;hormone replacement therapy;,;postmenopausal hormone therapy;, or;postmenopausal hormones;.

In the past, many doctors and their patients believed that MHT didnt just help with hot flashes and other symptoms it had important health benefits. But well-conducted studies have led many doctors to conclude that the risks of MHT often outweigh the benefits.

This information covers only how MHT can affect a womans risk of getting certain cancers. It does not cover other possible risks of MHT such as heart disease or stroke.

You can use this information when you talk to your doctor about whether MHT is right for you.

Recommended Reading: How To Dose Melatonin For Sleep

Tips To Help Prevent Estrogen Dominance A Risk For Breast Cancer In Women And Men

Low estrogen levels in women can cause weight gain, mood swings and headaches. It also raises the risk for cardiovascular disease, osteoporosis and dementia. And in men it may raise body fat, lower sex drive and contribute to erectile dysfunction.;

Seems awful. But there is one bright spot lower levels of estrogen also lower your risk for breast cancer as well as other estrogenic cancers such as ovarian, uterine, thyroid and prostate. A pooled analysis involving nine studies suggested that having high levels of the estrogen estradiol doubles your risk for breast cancer, according to the Susan G. Komen Foundation.

There are different types of estrogen, says Dr. Andrea Klemes, endocrinologist and chief medical officer, MDVIP. Low levels of one type can lead to a host of health issues, while high levels of another type raise the risk for cancer.Estrogen is a group of female hormones comprising estrone, estradiol, estriol:

Genetics are involved in breast cancer but not as much as you might think. Less than 15;percent of breast cancer cases have familial ties, according to BreastCancer.org. Hormones play a role in at least some types of breast cancer.;

However, estrogen also plays a critical role in the development of breast cancer, according to a study published in Cancer Letters. Researchers found that cells involved in estrogen-receptor positive breast cancer cells one of the most common forms of breast cancer — need estrogen grow.;

Estrogen Receptor Blockers Estrogen Receptor Blocker Drugs Attach Directly To And Block The Estrogen Receptors On Cancer Cells So That The Cancer Cells Cant Use Estrogen They Do Not Affect The Level Of Estrogen In The Body Estrogen Receptor Blockers Are Also Called Selective Estrogen Receptor Modulators

Hormone Therapy

Tamoxifen

Tamoxifen is the most commonly used anti-estrogen drug. It is used in post-menopausal and premenopausal women. Tamoxifen is given by mouth as a pill.

Tamoxifen is the hormonal therapy drug used most often to lower the risk that DCIS or LCIS will lead to an invasive breast cancer.

Tamoxifen very slightly increases the risk for uterine cancer, deep vein thrombosis and stroke. Doctors will carefully weigh these risks against the benefits of giving this drug before they offer it to women who have a personal or a strong family history of these conditions. Usually the benefits of taking tamoxifen outweigh these risks.

Fulvestrant

Fulvestrant is an anti-estrogen drug that reduces the number of estrogen receptors on breast cancer cells. It is given as an injection into the muscles of the buttocks.

Fulvestrant is used in post-menopausal women if the breast cancer has grown after they were treated with tamoxifen. It is also used in postmenopausal women with locally advanced or metastatic breast cancer that have never been treated with hormonal therapy.

Also Check: Will Low Estrogen Cause Weight Gain

What Are The Signs That Breast Cancer Has Spread

The symptoms of MBC can vary, depending on where the cancer has spread.

  • Breast cancer that has spread to the bones may cause pain, swelling, or bones that break or fracture easily.
  • Lung cancer metastasized from the breast can cause shortness of breath, breathing difficulties, chronic cough, and chest pain.
  • When breast cancer spreads to the liver, it can trigger abdominal pain, loss of appetite, nausea, unusually high levels of enzymes in the liver, and yellow skin due to jaundice.
  • Brain or spinal tumors caused by breast cancer thats spread can lead to persistent headaches, blurred or double vision, nausea or vomiting, seizures, and behavioral changes.

Its important to keep in mind that while several nonspecific symptoms, such as fatigue, weight loss, and poor appetite, may be related to MBC, they can also be caused by other factors, like depression or medication.

If you have concerns about specific symptoms, talk with your doctor to make sure they arent related to MBC.

Treatment for stage 4 or metastatic breast cancer will depend on where it has spread. It will also vary depending on the following factors:

  • the level of hormone receptors and/or HER2 in the tumor
  • gene mutations in the tumor
  • specific symptoms
  • whether women are still menstruating
  • overall health

For those with stage 4 breast cancer, the primary treatments are systemic or drug therapies. These options include chemotherapy, hormone therapy, immunotherapy, and targeted therapy, or some combination of the four.

Does Human Growth Hormone Increase Cancer Risk

In excess of 600,000 Americans will die this year alone due to some form of cancer. With such a catastrophic death toll, cancer consistently tops the list of leading causes of death in the United States. In addition to the sheer volume of new cancer cases each year, the increasing rate of cancer prevalence is equally worrying.

The chart below compares cancer deaths, the cancer death rate, and the age-standardized death rate.

Whereas just a few years ago the figure stood at a 1 in 3 chance for the typical person to develop cancer, that number has advanced to a greater than 50% chance that you, the reader, will be diagnosed with cancer at some point in your life. It may have already happened to you or someone you love.

The situation is dire but not hopeless; although we still have a lot to learn about how and why cancer spreads, modern medicine has afforded us a good amount of insight into how to effectively combat cancer. Understandably, many patients who are considering the restorative healing potential of HGH therapy in cases of deficiencies are concerned about possible cancer risks associated with HGH supplementation. In this article, well explore the complex relationship between HGH and cancer and what it could mean for hormone replacement therapy patients.

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Breast Cancer In Postmenopausal Women

Breast cancer is most common in postmenopausal women, and most breast cancers in postmenopausal women are hormone receptor positive.;As women age, the fat cells in their breasts tend to produce greater and greater amounts of an enzyme called aromatase. Aromatase promotes the production of oestrogen. Consequently, with age, the levels of oestrogen present in women’s breasts increases. This locally produced oestrogen plays a role in both the development and growth of breast cancer in postmenopausal women. Once established, the tumour acts to increase oestrogen levels to help it grow, with immune cells appearing to boost oestrogen production.;Recent studies have also identified a link between obesity and oestrogen production. Data demonstrating that obesity carries a two-fold increased risk of developing breast cancer in older women supports these findings. This makes sense considering that obese women have more of the fat cells responsible for producing oestrogens.

Does Hrt Cause Breast Cancer

Do Hormones Cause Breast Cancer? Let’s find out.

Taking HRT increases the risk of breast cancer.

  • The longer you use HRT, the greater your risk
  • Once you stop taking HRT, it can take up to 10 years for this risk to fall to about the same as if you had never taken it.;This will depend on the type of HRT and the length of time you were using it
  • Breast cancer risk is greater with combined HRT than with oestrogen-only HRT

Talk to your doctor when deciding to start or stop taking HRT, or if you are worried about HRT and breast cancer.

Read Also: Can Having Your Tubes Tied Cause Hormonal Imbalance

Epigenetics And Cancer Risk

Many inborn risk factors for cancer are epigenetic. Epigenetics refers to physical modifications to DNA that do not alter the DNA material itself but affect how cells interpret the data contained within. The interpretation of genes in the conduct of day-to-day physiological functions is called gene expression. Epigenetic mutations are often passed from parent to child. Scientists now better understand the dynamic relationship between epigenetic mutations and cancer growth.

For example, tumor-suppressor genes perform important work in the body by as the name suggests fighting the growth of cancerous tumors. In patients whose TSGs have been suppressed or otherwise inhibited by epigenetic changes, the stage is set for cancer growth. Therefore, maintaining awareness of who, if anyone, has been affected by cancer in your family is crucial to determining your risk factor. This is why most primary care physicians and oncologists request a thorough review of cancer incidence among family members in their initial evaluation process.

How Does Hormone Therapy Work Against Prostate Cancer

Early in their development, prostate cancers need androgens to grow. Hormone therapies, which are treatments that decrease androgen levels or block androgen action, can inhibit the growth of such prostate cancers, which are therefore called castration sensitive, androgen dependent, or androgen sensitive.

Most prostate cancers eventually stop responding to hormone therapy and become castration resistant. That is, they continue to grow even when androgen levels in the body are extremely low or undetectable. In the past, these tumors were also called hormone resistant, androgen independent, or hormone refractory; however, these terms are rarely used now because the tumors are not truly independent of androgens for their growth. In fact, some newer hormone therapies have become available that can be used to treat tumors that have become castration resistant.;

Recommended Reading: Which Hormone Makes Your Hair Grow

Eliminate Xenoestrogens As Much As Possible

Xenoestrogens are foreign or false estrogens or estrogen-mimicking compounds that majorly mess with our hormones. When the body encounters these xenoestrogens, it acts as though its been exposed to higher levels of our own internally-produced estrogens. This causes hormonal chaos.

How do we get exposed to these chemicals? Its largely through the products we choose to use in our homes and on our bodies . Ive written more about some of these compounds and how to avoid them in Whats hiding in your laundry soap?, Top 10 Toxic Skin Care Ingredients that Impact Hormonal Health, and Could Ingredients in Your Makeup Induce Early Menopause?

In these articles, youll find tips and suggestions for reducing your exposure to xenoestrogens like BPA, parabens, and phthalates, which can accumulate in breast tissue.

The other way to look at it is to pick products that are clean and safe, and dont require you to be a chemist to figure out the safety of each ingredient. We feature such products on our All Things We Love page.

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