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How Do You Get Bioidentical Hormones

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Does That Mean Compounded Bioidentical Hormones Are Safer

Bio-Identical Hormones – Should You Get On or Off Them?

“There is no reason to think that these bioidentical compounded would have a different safety profile than the FDA-approved ones,” Uhl says. She points out that some compounded pharmacies have gotten warning letters from the FDA for false and misleading claims about safety and other benefits.

Isaac Schiff, MD, chief of obstetrics and gynecology at Massachusetts General Hospital, agrees.

Schiff led an American College of Obstetrics and Gynecology committee that reviewed the scientific evidence on compounded bioidentical hormone therapy in 2005. That committee concluded that there wasn’t scientific evidence to support claims of increased efficacy or safety for compounded estrogen or progesterone regimens. The North American Menopause Society and the Endocrine Society have issued similar statements.

“It may be safer, but that study hasn’t been done yet,” Schiff tells WebMD. He says he would like to see a large, lengthy, rigorously designed study on the topic.

“I’m not inherently negative about it,” Schiff says. “I hope they’d be good … and if it turns out to be safer, fabulous. I would like, as a physician, to prescribe the safest hormones to my patients who want to be treated.”

Erika Schwartz, MD, a New York doctor who prescribes FDA-approved biodentical hormones and compounded bioidentical hormones, says there have been studies that support the safety of bioidentical hormones, compared to other hormone therapy.

How Are These Hormones Different From The Ones In Standard Hrt

Bioidentical hormones are as more ‘natural’ the big selling point to bioidentical hormones is that they are supposed to be the more natural option to HRT, because they are chemically identical to the hormones produced by your body. However, what many people dont realise, is that:

Standard HRT does contain hormones that are identical to our own hormones, and most importantly they are regulated for safety. Dr Heather Currie, chair of The Menopause Society;

Many of the standard HRT medications actually do already use hormones that are bioidentical.

Doctors don’t see a medical difference many doctors believe that, in fact, the effects of HRT and BHRT are very similar they carry the same health risks and have similar side effects. The main difference is that HRT is heavily regulated, whereas not all of BHRT is. This is a potential safety issue because the risks associated with unregulated medications are not known, and the levels of the hormones in each product are not controlled.;

You doctor can explain bioidentical hormones to you in person if you are interested in bioidentical hormones as a plant-based alternative to HRT, talk to your doctor in the very first instance. They will be able to advise you in your specific situation, and advise you on whether or not the treatment is safe.

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Why Should I Use Bioidentical Hormones

Over the last 100 years as we have doubled our life expectancy, the soft tissue glands which create our hormones are being forced to produce them longer than ever. Our increasingly stressful lives, poor nutrition, and lack of proper fitness result in declining levels of hormones in our bodies as well. Men and women have successfully used bioidentical hormones for decades. Men suffering from the symptoms of andropause or women suffering from menopause or perimenopause can turn to bioidentical hormones to replace the natural hormones that have declined as their bodies have aged. In well-known medical journals, researchers have reported that bioidentical hormones, estrogen, progesterone, and testosterone, are not only safe but also have a positive impact on preventing conditions such as heart attack/disease, stroke osteoporosis, osteoarthritis, colon cancer, Alzheimers, and periodontal disease.

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What We Learned From The Whi

The findings of the E+P arm of the WHI that were published in 2002 dramatically changed the prescribing practices of physicians in the United States. Before the trial demonstrated adverse cardiovascular disease events and a 26% increased risk of breast cancer in female participants, the number of women for whom E+P was prescribed had been steadily increasing, from 58 million in 1995 to 90 million in 1999. From 1999 to 2002, the numbers stabilized; however, within 3 months of publication of the WHI findings, prescriptions for E+P decreased by 63%. Many women stopped HT and some sought out alternative therapies for treatment of symptoms associated with menopause. In addition to their effect on physician-prescribing patterns, the WHI findings changed the perceptions of patients about the trustworthiness of the advice dispensed by physicians. A small survey of 97 women conducted in 2005 demonstrated that all the participants had heard of the WHI; a substantial number expressed a loss of trust in the information about HT that they received from their physicians.

Conventional Vs Bioidentical Hormones

Bioidentical hormone replacement therapy omaha ...

There is a difference between bioidentical hormones and those used in conventional hormone replacement therapy . Bioidentical hormones are chemically identical to those our bodies secrete naturally. They come from plant estrogens.

But, the hormones for traditional HRT come from pregnant horses urine and other synthetic hormones. Those who support bioidentical hormones claim that the products are safe. This is because the composition of these hormones is identical to the natural hormones that the body produces.

But most experts believe that HRT and BHRT have similar risks. The risk may even be higher in compounded bioidentical hormones. There is still no proper evidence to prove that BHRT has more efficacy than HRT.

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Disease Prevention For Women

Estrogen is responsible for so many functions within the female body that its impossible to list them all here. What we can say, however, is that normalizing this hormone with therapy can lead to:

  • Stronger blood flow throughout the body
  • Potential drop in blood sugar levels
  • Possible decrease in Alzheimers incidences
  • 37% less risk of developing colorectal cancer
  • 37% fewer hip fractures caused by osteoporosis

Who Needs Bioidentical Hormones

Due to the controversy still surrounding the safety of bioidentical hormones, most women going through perimenopause may want to consider other treatment options first.

Not all women respond well to traditional treatments, however. In these cases, women may consider bioidentical hormones as potential alternatives.

Also, women who have tried other medications may want to consider changes in their lifestyles before starting bioidentical hormone therapy. Some additional measures to try can include:

  • lotions
  • tablets

The application of a treatment is supposed to restore the natural hormones that younger women have, but that reduce as they age.

When under a doctors care, a woman will be tested for hormone levels, typically by sampling saliva or blood. The doctor will determine what hormones the woman needs and a pharmacist will mix a treatment of supposedly natural ingredients.

During her treatment, a woman will have her hormone levels assessed several times to check for balance.

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Which Bioidentical Hormones Should You Take

The molecules naturally produced in the human female body for which we most often seek replacement include:

  • Estrone , estradiol , and estriol
  • Progesterone
  • Testosterone
  • DHEA, an adrenal precursor to testosterone.

These truly natural hormones are available by prescription.;; Estradiol is available as Estrace pills, Estrace vaginal cream, or transdermals as the Vivelle Dot, and Climera. (Pharmaceutical companies have been able to patent the delivery system on these hormones, though the hormone itself is still bioidentical.; Estriol is available only through formulary pharmacies.; Most women do fine with just estradiol plus or minus some progesterone. And sometimes a bit of testosterone, which is available by prescription as AndroGel.

How Do I Get Bio

What are Bioidentical Hormones for Menopause? – 23

You can get bio-identical hormones in 3 ways:;

1) A patented commercial preparation from a regular pharmacy by prescription, ie: Vivelle patch, Prometrium.;

2) A non-patented preparation made by a special compounding pharmacy, also by prescription.;

3) Progesterone cream and DHEA are available over the counter without a prescription.

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Custom Compounding Is Misleading

To buy bioidentical hormones, you can’t just go to any chemist. First, you see a health practitioner. They will often conduct a saliva test, or order a blood test to check your hormone levels. You then take their prescription for biodentical hormones to a compounding pharmacist, who makes up the hormones especially for you.

This customised compounding makes women think that bioidentical hormones are better suited to their specific hormonal imbalances, but this is untrue. In fact, saliva tests are not considered a reliable method for establishing hormone levels. Blood tests are also not necessarily reliable, as women’s hormones during perimenopause and menopause can change from day to day, or even hour to hour, says Dr Newman.

“Women respond in different ways to this hormonal chaos,” she says. “For some women it makes no difference to how they feel, whereas other women may suffer severe symptoms, despite having similar blood results.”

The cost of bioidentical hormones is also considerably higher than conventional HRT.

Why Do Men Need Testosterone Replacement

As men age, production of the hormone testosterone begins to decline and they experience symptoms of low testosterone. Testosterone is the hormone that is responsible for maintaining mental focus, energy, metabolism, muscle mass, fat levels, and sex drive. By balancing a mans hormones with bioidentical hormone replacement therapy, men can restore their vitality and reduce the symptoms of andropause.

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Birth Control Pills Vs Bioidentical Hormones

Lastly, it’s worth touching upon birth control pills and how they fit into the conversation.;

You may be wondering whether or not birth control pills are bioidentical given that they are frequently prescribed by doctors without a second thought.;

The answer is NO.;

And here is where things get interesting.;

Doctors have no problem prescribing birth control pills to YOUNG women which are filled with Frankenstein hormones that “look” like estrogen and progesterone.;

And, by the way, these birth control pills contain doses that are so high that they completely shut down your body’s ability to produce its own estrogen and progesterone as a side effect.;

But then these same doctors absolutely REFUSE to prescribe bioidentical progesterone to women who are in menopause and have depleted levels of both estrogen and progesterone.;

They won’t even prescribe LOW DOSE bioidentical estrogen or progesterone for these women citing the “dangers” of such therapy.;

Do you see the problem here?

These doctors are perfectly fine prescribing high doses of fake hormones to women which are associated with all sorts of risks, including an increased risk of breast cancer .;

But won’t do the same for women who actually need it.;

When it comes to birth control methods, the use of bioidentical hormones doesn’t really come up.;

You can use bioidentical progesterone to help with some hormone imbalances, but you wouldn’t want to use it to prevent conception.;

Discussion Point : Estriol Is A Weak Estrogen But Not Necessarily A Benign Estrogen

The Pros and Cons of Bioidentical Hormones

It is common for BCHT to include E3, although no FDA-approved products contain estriol.,, In 2008, the FDA issued a warning that E3 may not be compounded without an FDA investigational new drug application.

As a part of BCHT, E3 may be combined with E2 and/or estrone in varying proportions. Such preparations are called Bi-est or Tri-est . Bi-est 2.5 mg refers to a preparation containing 2 mg of E3 and 0.5 mg of E2.

Estimates of E3’s potency vary greatly, ranging from one-tenth to one-one hundredth of E2, and is likely to vary by tissue. If E3 is credited with the highest possible potency, ie, one-tenth of E2, Bi-est 2.5 mg, containing 2 mg E3 and 0.5 mg E2, may actually have 2 mg E3 equipotent to only 0.2 mg E2. This is contrary to what might be suspected based on apparent product composition, wherein E3 seems to be the main component.

E3 it is considered a safer estrogen, based on some earlier rodent studies, but this has not been confirmed in clinical trials. Proponents have claimed that E3 might decrease the risk of breast cancer by blocking estrogen receptors, but E3 binds only weakly and transiently to these receptors. Once it dissociates, the receptors remain available for E2 binding. If E3 is administered with increased frequency to achieve adequate amounts in circulation, E3 binding to the estrogen receptor has been shown to result in the stimulation of the breast and uterine tissues, similar to the effect of E2, and any potential protective effect may be lost.,

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The Dangers Of Compounded Bioidentical Hormone Replacement Therapy


The menopause is a normal life event for women, not an illness or a medical condition. However, the effects of the menopause often have a negative impact on womens wellbeing and quality of life, and are frequently underestimated by noth women and their doctors. Furthermore, the low estrogen levels and other biological changes that occur in menopausal women are also associated with an increased risk of cardiovascular disease, osteoporosis, type 2 diabetes, and dementia.

Around 75% of menopausal women experience symptoms, with around one-third of these experiencing severe symptoms which are having a negative effect on their lives, both at home and at work.

Over the past two decades, there has been a huge amount of confusion regarding hormone replacement therapy . We now have clear, evidence-based guidelines available to ensure women have individualised care and treatment for their perimenopause and menopause.,

Bioidentical Hormones: What They Are And Their Best Uses

Written by Support on . Posted in Bioidentical Hormones, Menopausal Care.

For many people, the body starts to show the wear and tear of the years that have passed around middle age. As you age, your natural production of hormones may become impaired. Your body may start to produce higher levels of some hormones and lower levels of others. When hormone levels are lower than they normally are and bear in mind that normal is different for every single person your body may develop uncomfortable symptoms and unhealthy conditions.; Bioidentical hormone therapy can help you feel better.;

Bioidentical hormones are man-made hormones that operate in a very similar way to the hormones produced by the human body. They are often used in men and women whose hormone production is low or out of balance.;

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Bioidentical Hormone Replacement Therapy


Your bodys hormones control most of your basic bodily functions. They serve as an internal communication system between cells throughout the body. They coordinate everything from digestion and growth to your appetite, immune function, mood, and libido. So, when your hormones are out of balance, even slightly, it can have a big impact on your health and well-being.

Often, when peoples hormones drop or become unbalanced, they turn to hormone replacement therapies to ease symptoms. One such therapy, bioidentical hormone replacement therapy , has gotten a lot of attention in recent years. It promises a natural solution to hormone issues. But what exactly is BHRT, and hows it different from other hormone replacement therapies?

Read on to learn all you need to know about BHRT, its benefits and risks, and whether it may be right for you.

Summary Of Key Terminologies

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cBHRT: Compounded Bioidentical Hormone Replacement Therapy: Precise duplicates of human hormones which are produced by specialist pharmacies and do not follow the same MHRA regulatory pathway as conventional rBHRT

rBHRT: Regulated Bioidentical Hormone Replacement Therapy: Precise duplicates of human hormones developed in a conventional way by the pharmaceutical industry and authorised by the regulators such as the MHRA in the UK

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How To Talk To Your Doctor

I receive letters almost daily from women who have taken the initiative to offer their health care providers information on bioidentical hormones. If you want to use bioidentical hormones as replacement therapy, here are the salient points to know and share with your doctor about bioidentical hormones:

  • They have been prescribed by doctors for many years.
  • They are readily available through formulary pharmacies.
  • They are easily titrated to suit a womans individual needs.
  • They are readily absorbed and utilized.
  • They are safe and effective.

Many formulary pharmacists work in partnership with physicians to provide individualized hormone-replacement solutions. You may want to call a local formulary pharmacy to consult with a knowledgeable pharmacist to develop your customized plan.

What About Hormone Pellets

Dr. Rebecca is quite adamant in her objection to pellets. Why? Because they can have pretty awful side effects, and once the pellets have been implanted, side effects or no, they cant come out.

Hormone pellets are tiny pellets no larger than a grain of rice that are surgically implanted under a patients skin or in muscle tissue. The pellets are intended to give a slow, continuous release of hormone. DHEA testosterone pellets are particularly popular for women hoping to revive their sexless marriage after menopause.

The problem with pellets is, again, theyre not FDA-regulated, and weve seen that they can give an exceedingly high dose of hormone depending on where and how deeply they were implanted. Many women suffer significant side effects as a result, especially with testosterone. Women think theyll get their libido back, have more energy, feel younger, and they may but they may also grow a beard, develop acne, have clitoromegaly, where the clitoris grows and becomes very like a small phallus, and develop a deeper voice. Those last two dont go away when the testosterone does. The small phallus and the deep voice are forever.

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Discussion Point : Bioidentical Does Not Mean Natural

Bioidentical refers to the structure of hormones; bioidentical hormones and endogenous hormones have exactly the same chemical and molecular structures. However, natural refers to the of hormones. Natural hormones may not be bioidentical. For example, phytoestrogens are plant-derived, natural estrogens found in soy products like soy milk, tofu, and tempeh. These phytoestrogens are structurally dissimilar to the endogenous human hormones and result in weak receptor binding and modest clinical effects.

Hormones used in BHT, which are structurally similar to endogenous human hormones, are generally derived from soy and yams, but they need to be commercially processed to become bioidentical. Thus, bioidentical hormones are not completely natural, and natural hormones are not necessarily bioidentical .

Bioidentical Hormones: Misconceptions and Facts

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