Estrogen Hormone Therapy Treatment
The hormone, estrogen, influences most feminine characteristics. It can be given by pill, injection, or skin preparations like patches, sprays, gels, and creams. Pills are effective, cheap, and convenient, but if youre older than 35 or smoke, their safety can be compromised. Patches are also safe and effective, but you will need to wear them all the time. They can also irritate the skin. We generally start Estrogen at dose of 2 mg/day and titrate the dose to achieve the desired results while limiting negative side effects.
Most transwomen take in estrogen via injection. Injections can cause fluctuating or high estrogen levels, resulting in weight gain, mood swings, anxiety, migraines, or hot flashes. There isnt much information with regards to taking high levels of estrogen over a long time.
Contrary to popular belief, relatively small doses of estrogen can actually have the most effect on the transition. Taking higher doses dont necessarily make the changes happen quickly and may even harm your health. After going through orchiectomy or genital surgery, the estrogen dosage should be lowered by the doctor. Without testicles, you will need less estrogen for good health and feminine characteristics.
You will periodically need to get liver function, cholesterol, and diabetes screenings to check on your health while on estrogen.
What Are The Emotional And Intellectual Effects Of Estrogen
People are very different so their emotional and intellectual changes vary widely. People taking estrogen have reported:
- Feeling more emotional and more in touch with their feelings
- Crying more easily
- Depression or sadness
- Thinking differently, having different ways of looking at things
- Feeling more like myself when taking a hormone that aligns with gender identity; feeling more comfortable in ones body
How Hormones Work For Male To Female Transitioning
Hormones are chemical messengers produced by one part of the body totell cells in another part of the body how to function, when to grow, whento divide, and when to die.
They regulate many functions, including growth, sex drive, hunger, thirst, digestion, metabolism, fat burning, and storage, blood sugar and cholesterol levels, and reproduction.
Sex hormones regulate the development of sex characteristics includingthe sex organs that develop before we are born and also the secondary sex characteristics that typically develop atpuberty .
The three categories of sex hormones that naturally occur in the body are:
Androgens: testosterone, dehydroepiandrosterone ,
Generally, males 2 tend to have higher androgen levels, and females 2tend to have higher levels of estrogens and progestagens.
There are various types of medication that can be taken to change thelevels of sex steroids in the body. Changing these levels will affect fatdistribution, muscle mass, hair growth, and other features that areassociated with sex and gender.
For MTFs this can help make the body.
2. The binary terms male, female, masculine, feminine, masculinizing, and feminizing dont accurately reflect the diversity of trans peoples bodies or identities.
But in understanding how hormones work for trans people, it is helpful to understand how testosterone works in typical mens bodies, and how estrogen and progesterone work in typicalwomens bodies.
pill skin patch or gel injection
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How Long Does Hormone Replacement Therapy Last
Whenever you begin taking a new prescription, there is a period where it needs to build up in your system. This can be a few hours to a couple of days.
Then, once you hit the optimal level, the type of replacement therapy will dictate how long you remain at peak level. Pellets give you the longest-lasting average level ranging from 3 to 6 months, followed by injections that typically last 1-2 weeks. Patches may last a few days, and pills a single day. Creams and gels only last a few hours.
When you choose a hormone replacement therapy, factor in how often you need to go to the doctors office, travel expenses, how often do you need a real application of the treatment, and any insurance deductibles, co-pays, or unexpected expenses. And, ask your doctor about the out-of-pocket costs, which may surprise you how much lower they are.
HTCA providers are trained to bioidentical pellet therapy, plus keep the additional costs to a minimum. They enjoy the ease of prescribing the pellets and how fast and consistently their patients experience relief.
In our opinion, even though pellets only have a cash payout option, the ease of use and the low frequency of doctors visits and application requirements needed is the most convenient and cost-effective method of treatment. You can search our list of doctors to find one near you.
Male To Female Hormone Transition Guide
While there are some health risks involved with hormone therapy, it can have positive and important effects on trans peoples quality of life.
Knowing what you can expect will help you work with your health care providers to maximize the benefits and minimize the risks.
The purpose of this website is to: explain how hormones work describe the changes to expect from MTF1 hormones, and outline risks and possible side effects give you information about how to maximize the benefits and minimize the risks
1. We use MTF as shorthand for a spectrum that includes not just transsexuals, but anyone whowas assigned male at birth and who identifies as female, feminine, or a woman some or all ofthe time.
Some non-transsexuals may also want hormone therapy, and may not identify or live as women.For this reason, we use the term MTF instead of trans women.
This website is written specifically for people in the MTF spectrum who are considering taking hormones.
It may also be a helpful resource for partners, family, and friends who are wondering how hormones work and what they do.
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Facial Feminization Surgery Surgery Cost
In order to correct certain gendered features in the face, some transgender people will undergo facial cosmetic surgery, called facial feminization surgery or facial masculinization surgery . Neither FFS nor FMS is a single procedure by itself. Instead, they represent a wide variety of procedures that contribute to sexual characteristics in the face. As a result, the price that you can expect to pay for FFS or FMS will vary wildly depending on the surgeon you choose and the procedures they perform. According to individuals that we spoke to who had sought out these procedures, surgery could cost you between $5,000 or $50,000, although most surgeries are likely to fall somewhere in the middle, as few people only get a single small procedure or an extremely large number of procedures.
Effects Of Testosterone And Estrogen
Many trans men seek maximum virilization, while others desire suppression of their natal secondary sex characteristics only. As a result, hormone therapy can be tailored to a patients transition goals, but must also take into account their medical comorbidities and the risks associated with hormone use.
The following changes are expected after estrogen is initiated: breast growth, increased body fat, slowed growth of body and facial hair, decreased testicular size and erectile function. The extent of these changes and the time interval for maximum change varies across patients and may take up to 18 to 24 months to occur. Use of anti-androgenic therapy as an adjunct helps to achieve maximum change.
Hormone therapy improves transgender patients quality of life . Longitudinal studies also show positive effects on sexual function and mood . There is biologic evidence that may explain this. Kranz et al. have looked at the acute and chronic effects of estrogen and testosterone on serotonin reuptake transporter binding in trans men and women. SERT expression has been shown to be reduced in individuals with major depression . Kranz et al. found that androgen treatment in transmen increased SERT binding in several places in the brain and anti-androgen and estrogen therapy led to decreases in regional SERT binding in trans women. These types of data are preliminary, but do point to the important role of hormone therapy in patients who suffer from gender dysphoria.
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How Is Gender Identity Disorder Treated
The whole treatment process is known as triadic therapy, which is a progressive strategy, consisting of three critical elements ;real-life experience, hormonal therapy of the desired gender and finally, sex reassignment surgery. As the person advances through this sequence of therapy with increasingly irreversible effects on their body , it becomes increasingly difficult to revert to their birth sex. It is therefore important that hormonal therapy is undertaken in close collaboration with a mental health professional who is experienced in the assessment of people with gender identity disorder, ideally working closely with the endocrinologist to deliver treatment.
The aim of treatment is to suppress the production of the sex hormones of the persons birth gender and to give the hormones of the desired gender in order to produce the secondary sexual characteristics of that desired gender.;Following hormonal treatment, surgery is also often used to modify the genitalia and breasts to alter their appearance to that of the desired gender.;This is known as;gender reassignment surgery.;
After surgery, hormone treatment needs to be continued to prevent the complications of not having sex hormone production such as brittle bones or early heart disease.
Surgery For Trans Men
Common chest procedures for trans men include:
- removal of both breasts and associated chest reconstruction
- nipple repositioning
Breast implants for trans women are not routinely available on the NHS.
Gender surgery for trans men includes:
- construction of a penis
- construction of a scrotum and testicular implants
- a penile implant
Removal of the womb and the ovaries and fallopian tubes may also be considered.
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Symptoms Of High Estrogen Levels In Men
Here are some of the main symptoms of high estrogen levels in men:
- Infertility. Estrogen is one of the hormones your body uses to produce sperm. High estrogen levels can slow down sperm production and make it harder to create healthy sperm.
- Gynecomastia. Increased estrogen can cause more breast tissue to develop than normal. High levels can lead to the development of a condition called gynecomastia. This happens when the amount of breast fat tissue is abnormally high.
- Erectile dysfunction . Increased estrogen levels can affect the balance of hormones that are needed to help get an erection and stay erect. This is especially true if you also experience low testosterone.
- Slowed growth. Too much estrogen can result in short stature or delayed puberty in boys.
- Epiphyseal closure. This can happen in adolescents with high estrogen, causing boys to have short stature.
Other possible symptoms of high estrogen that may happen along with other hormone imbalances include:
- reduced sex drive
Male And Female Muscle: Similar But Different
Men and women have many things in common. However, subtle but important things separate us when it comes to building muscle.
Many things have a say in how much muscle you can gain and how fast. Anabolic hormones and enzymes in our muscles tell our bodies to flip the switch and add muscle mass. Lifting weights increase muscle gain and muscle breakdown, and when the gain is larger than the breakdown over time, your muscles grow bigger and stronger.
Males and females are quite different in some of these areas, and many people probably think that the advantage is in the male corner. The weights dont care about your sex, though. We all benefit from strength training. We get bigger and stronger, and healthier.
Is it a myth that females have a harder time gaining muscle mass and strength, or can you expect to gain the same regardless of your sex?
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How Often Do You Need To Visit The Doctor
Every time your prescription renews, you will need to visit the doctor. There will be an office charge that may or may not be in your co-pay. Most of the time, you will also need a test to evaluate your hormone levels. A blood test is typically the best in the form of testing to identify your hormone levels and is used to verify the level of hormone therapy you are receiving is accurate. This test may range from $80 to well over $500, depending on what the doctor needs to testblood test range from$80 to $200.
Problematic Aspects In Relation To Sex Reassignment Treatment
It appears obvious that maintenance of steroid hormone levels in the physiological range of the desired sex should be achieved in individuals with GD prior and post-SRS . The Endocrine Society recommends monitoring patients every 3;months during the first year of therapy and once or twice yearly thereafter . For CHT to be well tolerated, it is necessary to perform the hormonal administration in a highly individualized scheme in terms of timing, doses and modes of administration . Treatment can be considered successful if it relieves distress or facilitates substantial improvement in function and well-being of the patient .
The hormonal therapy in MtF subjects lasts 6.0;years on average . Based on expert opinion, however, patients tend to follow their self-controlled individual regimes as estrogen- and androgen-formulations are easily available via the Internet, over the counter, without prescription in certain settings, and through veterinary supply . However, subjects should be strongly discouraged from inducing supra-physiological hormone levels due to serious side effects . According to Leinung et;al. , 9.8% of male-to-female transsexuals started hormonal therapy without prescriptions from a physician and nearly all admitted of initiating hormonal therapy without medical supervision . This is surprising as one of the three inclusion criteria of the WPATH for GD therapy is the ability to take hormones in a responsible manner .
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Lower Doses And Temporary Use
For some trans people, being on a lower dose of feminising hormones, or using them occasionally or temporarily is a part of how they seek to hormonally affirm their gender.
It can be difficult to try and implement one feminising change and not another, as once a hormonal threshold is reached, a range of secondary sex characteristics will begin to change.
This is especially the case for breast growth, which may occur even at lower estrogen levels .
Consultation with a specialist Endocrinologist may be helpful.
The use of hormonal suppression without gender affirming hormonal therapy can lead to adverse health effects, and so is to be undertaken carefully, and with regular oversight.
It is possible to achieve testosterone and estrogen hormone levels that are between the male and female ranges. However, at this point, there is little evidence for this practice as most research only considers binary gender options.
A Guide To Transgender Health, Heath R, Wynne K 4
Meeting With A Therapist
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Where Can I Buy Male To Female Hormones
Transfemme® male to female hormones in pill and cream forms are available online on this website. Transfemme is a completely natural system to feminize the male body to varying degrees depending on which products you use and the dosages. We recommend calling one of our advisors on our Customer Success Team at or email us at
To My Surprise I Found That As My Body Began To Change On Hormones So Did My Sexual Orientation
In March of 2015, I made the huge step to go on hormones and start the process of transitioning from male-to-female through the use of Hormone Replacement Therapy, otherwise known as HRT. I was excited, but there were more than a few surprises in store for me as the months went on, a few of which I decided to share.
1. My Sexual Orientation Flipped
In March, if I had to describe my orientation, I would have said I was almost completely attracted to women, with slight wiggle room for the occasional crush on a dude. To my surprise, I found that as my body began to change on hormones, so did my sexual orientation. I was more and more attracted to men, progressing from more physically attracted to women, but more psychologically attracted to men, to finally where I am now, which is almost completely physically and psychologically attracted to men, with slight wiggle room for the occasional crush on a girl. I read up on this phenomenon, and it’s not uncommon among those who undergo transition, but I wouldn’t have minded someone letting me in on the fact this could happen!
2. My Libido Diminished Dramatically
3. My Experience of Arousal Transformed
4. Skin Sensitivity
5. Stretch Marks
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