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Is Hormone Therapy For Menopause Safe

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Early Menopause Hormone Therapy May Benefit Some Women: Study

Menopause – Is Menopausal Hormone Therapy (HRT) Safe?

Amanda GardnerHealth Day Reporter

Wednesday, October 3 -According to a new survey Hormone replacement therapy, Used to mitigate Hot flashes And other symptoms menopauseTaking small doses in a short period of time may be safe for young menopausal women.

woman Ive avoided this type of treatment since the breakthrough Womens health In the initiative survey, breast cancer, Heart disease Other health problems in women taking synthetic forms of estrogen and progestin Progesterone.. The study was discontinued early due to the results published in 2002.

However, the study will be presented at the North American Annual Meeting on Wednesday. menopause The Society of Orlando, Florida has discovered an oral form of estrogen Or as a patch , And progesterone did no harm heart In that it was raised blood pressure Also Arterial sclerosis..

Progesterone is added because only estrogen can be promoted Uterine cancer..

In another part of the study, hormone replacement therapy is mood and depressionDiscovered by researchers at the University of Wisconsin School of Medicine and the Faculty of Public Health. As the Womens Health Initiative showed, it didnt worsen memory, researchers said in a college news release.

A new study funded by the Phoenix-based Kronos Institute for Longevity breast cancer Rate, which is one of the main concerns of women considering hormone replacement therapy.

I still say the conclusion is whether you need to take Dont take it, Brooks said.

Genitourinary Syndrome Of Menopause

Genitourinary syndrome of menopause refers to bothersome genital symptoms from changes in the vulva, vagina, and lower genital tract that are caused by diminished estrogen. This condition affects up to one-half of women during menopause.28 In 2014, a consensus conference endorsed the new term genitourinary syndrome of menopause to replace the terms vulvovaginal atrophy and atrophic vaginitis, partly because the older terminology does not encompass the extent of genital tract symptoms many women experience.29 Decreased estrogen can cause several changes to genital anatomy that lead to patient discomfort. Thinning of the vulvar mucosa may cause vulvar burning, irritation, or constriction of the introitus, resulting in entry dyspareunia. Narrowing of the vagina and decreased lubrication can cause painful intercourse or coital bleeding.30 Diminished estrogen may also lead to recurrent urinary tract infections and urinary urgency.29 Genitourinary syndrome of menopause is often progressive without treatment.28

Treatment Options for Genitourinary Syndrome of Menopause

Estrace vaginal cream 0.01%

Treatment Options for Genitourinary Syndrome of Menopause

Estrace vaginal cream 0.01%

This review updates previous articles on this topic by Hill and Hill,35 by Carroll,36 by Morelli and Naquin,37 and by Cutson and Meuleman.38

Read the full article.

Hrt For Menopause Therapy

Hormone replacement therapy uses bioidentical hormones and can directly contribute to longevity, yes living longer, and lead to a significant improvement in your quality of life.11 Taking hormone replacement therapy early in menopause can promote memory, concentration, and cognition.

Research shows that progesterone supplementation can improve brain function as well as nervous system health. In combination, the hormones estrogen, progesterone, and testosterone can also help protect against long terms health risks like cardiovascular disease, stroke, cancers, and Type 2 Diabetes.

Once a woman hits her mid to late â30s, she can enter perimenopause, and her levels of estrogen, progesterone, and testosterone production will start to decline. Once she reaches menopause, circulating hormone levels are way off â in fact, her progesterone levels are so low that they are similar to levels normally seen in men.1

Progesterone is an often overlooked hormone, but it might surprise you to hear that progesterone acts as a natural antidepressant and can enhance your mood and relieve anxiety. It actually stimulates the brainâs âfeel-good,â center. So it makes sense then that when progesterone levels drop with menopause, anxiety can become a major menopause problem.5 Researchers have shown that replacing progesterone appears to be the most potent anti-anxiety hormone for menopausal women.6,7

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Estrogen Therapy And Cancer Risk

Endometrial cancer

In women who still have a uterus, using systemic ET has been shown to increase the risk of endometrial cancer . The risk remains higher than average even after ET is no longer used. Although most studies that showed an increased risk were of women taking estrogen as a pill, women using a patch or high-dose vaginal ring can also expect to have an increased risk of endometrial cancer.

Because of this increased cancer risk, women who have gone through menopause and who still have a uterus are given a progestin along with estrogen. Studies have shown that EPT does not increase the risk for endometrial cancer.

Long-term use of vaginal creams, rings, or tablets containing topical estrogen doses may also increase the levels of estrogen in the body. Its not clear if this leads to health risks, but the amounts of hormone are much smaller than systemic therapies.

Breast cancer

ET is not linked to a higher risk of breast cancer. In fact, certain groups of women taking ET, such as women who had no family history of breast cancer and those who had no history of benign breast disease, had a slightly lower risk of breast cancer.

Ovarian cancer

The WHI study of ET did not report any results about ovarian cancer.

To put the risk into numbers, if 1,000 women who were 50 years old took estrogen for menopause for 5 years, one extra ovarian cancer would be expected to develop.

Colorectal cancer

Lung cancer

ET does not seem to have any effect on the risk of lung cancer.

Menopausal Hormone Therapy And Cancer Risk

Research shows hormone therapy still safe menopause treatment

For decades, women have used hormone therapy to ease symptoms of menopause, such as hot flashes and sweating. This is called menopausal hormone therapy, and you may see it abbreviated as HT or MHT. You may also hear it described as hormone replacement therapy , postmenopausal hormone therapy , or postmenopausal hormones .

In the past, many doctors and their patients believed that MHT didnt just help with hot flashes and other symptoms it had important health benefits. But well-conducted studies have led many doctors to conclude that the risks of MHT often outweigh the benefits.

This information covers only how MHT can affect a womans risk of getting certain cancers. It does not cover other possible risks of MHT such as heart disease or stroke.

You can use this information when you talk to your doctor about whether MHT is right for you.

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Your Libido Might Dip Thanks To Menopause

Its not universal, but some people with menopause report decreased libido, says Dr. Pizarro. Issue is, its tough for doctors to figure out how to combat a lowered sex drivethe cause isnt exactly easy to pinpoint. For decades, weve blamed loss of libido on a womans ovaries or hormones, says Libido is such a complicated thing that goes way beyond issues of the ovaries, uterus, and hormones, says Dr. Pizarro.

Beyond whatever mysterious physiological changes might affect someones libido at this life stage, adjusting to menopauses physical changes might play a role. Adequate exercise helps make sure your blood is flowing properly, which is an essential part of getting wet during sex.

Venous Thrombosis And Hrt

Venous thromboses are blood clots that form inside veins. Women under 50 years of age, and women aged 50 to 60, face an increased risk of venous thrombosis if they take oral HRT. The increase in risk seems to be highest in the first year or two of therapy and in women who already have a high risk of blood clots. This especially applies to women who have a genetic predisposition to developing thrombosis, who would normally not be advised to use HRT.

Limited research to date suggests the increased risk of clots is mainly related to combined oestrogen and progestogen in oral form, and also depends on the type of progestogen used. Some studies suggest a lower risk with non-oral therapy or tibolone.

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Is Hormone Replacement Therapy Safe For Menopausal Women

Treatment is on the mind of most women as they work through the symptoms associated with menopause. Hot flashes, night sweats, and mood swings can be disruptive, and most people just want relief. Hormone replacement therapy for women was once commonly used to treat the symptoms associated with menopause, but then there were reports that the treatment was causing significant health risks.

With conflicting information, it may be hard to distinguish whether or not hormone replacement therapy is a safe solution. Lets take a better look at the facts.

Are You A Good Candidate For Hormone Pellet Therapy

Menopause – Is Menopausal Hormone Therapy Safe? (Vietnamese)

Before getting excited about what hormone pellet therapy can do to make your life better if you are menopausal, do bear in mind that not everyone is the perfect candidate for this kind of therapy. Numerous factors need to be taken into account.

First, you will most likely need to have your hormones measured on a daily basis for days 19 to 21 of your monthly cycle. This means you may have to be in the beginning stages of your transition. If you have an irregular cycle, have undergone a partial hysterectomy, ablation , or have an intrauterine device , you should be wary of considering hormone pellet therapy. Topical cream or patches may be a better choice for you. This is because determining the cycle of someone with an IUD or a partial hysterectomy is very difficult, so getting correct hormone readings is also difficult and could result in inaccurate estrogen readings.

Estrogen hormone pellet therapy may be a good choice for otherwise physiologically healthy women who find that topical creams or patches are not working. Younger women who have undergone a complete hysterectomy are also great candidates, as are women who tend to forget to apply their topical creams or patches.

Keep in mind that you would be considered a high-risk candidate for estrogen hormone pellet therapy if you have any of the following:

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Risks Of Estrogen Treatment:

  • Breast: If there is a personal history, or very strong family history, of breast cancer women should not take estrogen therapy. However, it is very important to understand the actual risk.

  • Endometrium: If there is a personal history, or very strong family history, of endometrial cancer women should not take estrogen. There was no increased risk of endometrial cancer with hormone replacement therapy in recent studies but, it is important to understand the risk.

  • Stroke: The likelihood of having a stroke can be reduced by using transdermal patches or creams rather than oral estrogen replacement .

  • Pulmonary Embolism: The risk of pulmonary emboli is reduced by using a transdermal patch or creams rather than oral estrogen replacement .

  • Summary

    Our current knowledge of estrogen, progesterone, and testosterone hormone replacement for perimenopause and menopause is that it is extremely safe. Winona takes safety very seriously. We use only the safest hormones and tailor the delivery system to the individual needs of each woman.

    We will ask a series of health questions to make sure you are a good candidate for hormone therapy. A womenâs health specialist will work with each individual patient to tailor a treatment that is both safe and effective.

    Is Hrt Risky For Women

    What do these two large randomized trials tell us then about the dangers of hormone replacement therapy for women? We can conclude that it is probably not safe to give women HRT who are more than 10 to 20 years from menopause. However, we cannot take the data and generalize it to younger women or to all women. We can only generalize it to the older women that were studied in these two trials.

    When I prescribe hormone therapy, the age where I focus tends to be symptomatic women who are 45 to 55, or within 5 to 10 years of their final menstrual period . However, before we proceed with treatment, we will have a conversation about the limited and flawed data we have from the WHI and other smaller trials.

    Another important issue is that we cant generalize about the hormone therapy used in the trials. The HRT used was conjugated equine therapy and medroxyprogesterone acetate. We cant take the data showing the increased risk of cardiovascular disease, stroke, and blood clots and apply that to all forms of menopausal hormone therapy.

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    Hormone Replacement Therapy And Breast Cancer Risk

    Hormone replacement therapy is approved to treat hot flashes and vaginal dryness related to menopause.

    The Women’s Health Initiative , a national women’s health study, showed that long-term use of hormone replacement therapy combining two hormones — estrogen plus progestin — raised women’s risk of heart disease, stroke, blood clots, and breast cancer compared to women taking a placebo.

    In the wake of those findings, the FDA recommended that menopausal hormone therapy using estrogens and progestins should be used at the lowest doses for the shortest duration to reach treatment goals.

    But how short is the “shortest duration”? And what about hormone therapy that only includes estrogen without progestin, a treatment plan typically limited to women who’ve had their uterus surgically removed ? And is the breast cancer risk linked to hormone therapy reversible? Those are some of the questions tackled by the two new studies.

    Tenderness Or Pain In The Breasts

    Is extended hormone therapy safe during menopause?

    A woman currently on her period can experience fluid build up in the breasts. This build up can also happen just before a period takes effect. The result is that the breasts can become swollen, tender, and sometimes even painful.

    As time goes on, women age and start to go through perimenopause . The hormonal changes that accompany perimenopause are always different, and can always affect the breasts differently.

    In turn, this can mean that the swelling, tenderness, and pain can still stick around during and after perimenopause. In fact, sometimes random spells of swelling, tenderness, and pain may start to kick in due to lack of a period and an increase in hormonal imbalances.

    The best suggestion to keep handy would be to wear a fitted sports bra when such symptoms start to occur. Keep one on you, in your purse or in your car, just in case the tenderness or pain becomes close to unbearable.

    It may also help to massage the breasts when they start to exhibit such signs and symptoms. Dont go too rough, though. Small, steady circles will ease the discomfort youre feeling the best.

    And as always, pair these two suggestions with over-the-counter pain medications and pain creams to maximize your self care.

    Dont forget, sore breasts after menopause is not entirely uncommon.

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    Some Troubleshooting Considerations For Hrt

    Compared to topical hormone creams, your end results may be better with hormone pellet therapy. Fewer hormones, for example, may be needed to get your hormone level into that of your pre-menopausal state. Topical creams alone do not get your hormone levels down to a premenopausal range. You may also have better results addressing your particular menopausal symptoms and have more stable hormone serum levels than with a topical cream, while also reaping excellent benefits for your bone health. Overall, hormone pellet therapy appears to be better suited to stabilize your hormones and address your symptoms.

    But too much estrogen is also not a good thing. This means that, before undergoing a new bout of hormone pellet therapy, you may first need to wait until the effects of the previous therapy wear off. Increasing the amount of progesterone you receive may also help to balance things out if needed. If you do not have enough progesterone, even the smallest amount of extra estrogen could land you with symptoms of estrogen dominance. This is why many healthcare professionals suggest that, when undergoing hormone pellet therapy, or any other type of HRT, you should also consider taking a progesterone supplement.

    But what do you do if you just happen to be the exception?

    Sometimes people may find they have certain unforeseen side-effects. Once more, talk to your healthcare practitioner. Perhaps your estrogen-progesterone ratio needs adjustment.

    What Are Your Options

    You should talk to a doctor about any symptoms of perimenopause. Irregular bleeding should be investigated to rule out cancer and fibroids, both of which become more common with age.

    Birth control pills or an IUD can be a good first-line hormone therapy for women in perimenopause. Plus, theres the added benefit of contraception, and women in their 40s are one of the highest risk groups for unwanted pregnancy, notes Dr. Wolfman.

    Hormones can be come in the form of oral tablets, patches or transdermal gels. For women whose main symptoms are vaginal discomfort, there are therapies specific for the vagina in the form of creams, rings or tablets.

    For women who have symptoms during certain points in their cycle, physicians might add other medications or hormones for a few days a month on top of birth control. If the symptoms are primarily around mood, for example, other medications or cognitive behavioural therapy may be helpful, said Dr. Wolfman.

    Theres no one-size-fits-all approach to hormone therapy for perimenopause. It becomes an individual decision based on a woman’s personal risk, her family history and goals. So its a long discussion, she said.

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    Is Hormone Therapy A Safe Treatment For Menopause

    The narrative surrounding estrogen and progesterone prescriptions has changed over and againso where do we currently stand?

    We understand if the whole concept of hormone therapy has given you whiplash. In the ’90s, a prescription was standard to fight insomnia, hot flashes, vaginal dryness, and other not-so-fun menopausal side effects. Experts also thought it could reduce the those the risk of heart disease for those predisposed to the conditionas well as the bone fractures that come with losing estrogen over time.

    By the early 2000s, the tide had turned. Women’s Health Initiative hormone therapy trials found that taking estrogen plus progestin made breast cancer, stroke, heart disease, and blood clots more likely, and that estrogen alone upped odds of a stroke.

    But then, starting in 2006, new findings began to emergenamely thanks to a publication by the Nurse’s Healthy Study, which found that women who began HT shortly after the onset of menopause reduced their risk of coronary heart disease by 30 percentthis time showing that hormonal therapy’s benefits outweighed its risks for most healthy women under age 60 . If you fall into this demographic, the pros of this type of treatment may make it worth your whilewhich means it might be time to schedule a trip to the doctor.

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