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When Testosterone Therapy Might Help
Men who are no longer interested in conceiving may benefit from safe, monitored testosterone replacement therapy. Some patients with genetic issues that cause subfertility, such as Klinefelter’s syndrome, may also benefit.
- Lose a few pounds: Approximately 30% of obese men have low-T. Since muscle burns more calories than fat, the more muscle you have, the less likely your body is to store excess calories as fat. However, some research suggests that low-T contributes to weight gain it’s a vicious cycle. Start by cutting belly fat, which is good for your heart health and general wellness.
- Eat a healthy diet: For full-body health and hormone balance, consider the Mediterranean diet, which focuses on lean proteins, healthy fats, and plant-based foods. Also enjoy foods that are high in vitamin D, which supports testosterone production, strong bones, and mood. Some of these include eggs, salmon, and mushrooms.
- Rethink online viewing habits: Pornography is readily available online and it can perpetuate skewed expectations for what masculinity and sexual virility should feel like. Your body was not designed to perform sexually for hours on end what you’re seeing on the screen is cinematography, not reality.
Libido And Erectile Function
A common indication for testosterone therapy is treatment of decreased sexual desire or erectile dysfunction. A systematic review found 23 randomized trials of testosterone therapy’s effects on libido 13 trials showed some benefit, eight showed no benefit, and two had mixed results.12
Although evidence regarding erectile dysfunction is mixed, young men with hypogonadism and erectile dysfunction appear to benefit from testosterone therapy.13 Some studies have shown improvement in erectile dysfunction in older men and men with comorbid conditions,14,15 whereas others have not.12,16,17 Moreover, even in positive studies, the effect of testosterone has been smaller than the effect traditionally reported with phosphodiesterase-5 inhibitors,14 suggesting that testosterone should not be first-line treatment for erectile dysfunction. There is some evidence supporting the use of testosterone therapy as second-line therapy in men with low testosterone when phosphodiesterase-5 inhibitors are ineffective.18,19 There is no evidence that testosterone improves erectile function in men with normal testosterone levels. As part of the Choosing Wisely campaign, the American Urological Association says physicians should not prescribe testosterone therapy for men with erectile dysfunction and normal testosterone levels.20
Low Testosterone In Women
Low testosterone can also occur in women, and when it does, it usually affects the womans health. Testosterone performs several functions in a womans body. This includes:
- Red blood cells production
- Influences the production and activity of the follicle-stimulating hormone that can affect reproduction.
- Enhancement of libido.
A study by the Australian Department of Health & Human Services has shown that testosterone levels in women is age-dependent. And so, by the time a woman attains the age of 40, her sex hormone levels would have decreased by 50%.
Research is still ongoing on low testosterone in women. A lot is yet to be understood about this condition in the female gender. Nevertheless, new treatments are being developed treatments that will be very effective in women experiencing this condition.
What causes low testosterone in women?
Unlike men, testosterone in women is produced by several tissues and glands. These are:
- Adrenal glands
- Peripheral tissues
The thing is, most women will continue to produce testosterone and other hormones irrespective of whether they are in the pre-or postmenopausal years. Medical researchers have therefore hypothesized that women experiencing low testosterone levels may have some genetic alterations or defects that affect the production of DHEA-S and DHEA. Both substances are precursors to testosterone.
Common Signs Of Low Testosterone
Symptoms of low testosterone can be subtle and easy to disregard or attribute to another cause. Many men are under the mistaken belief that erectile dysfunction and decreased libido are the primary signs of low T, but the hormone problem can cause widespread symptoms. Not all men with low T develop sexual side effects.
The most common symptoms of low testosterone include:
- Hair loss, which tends to be rapid
These symptoms can quickly affect relationships and quality of life, especially among younger men.
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Treatments For Low Testosterone In Younger Men
Best treatment for low T level depends on its cause. The treatment sometimes include replacement therapy whereas sometimes losing weight can help to get rid of it.
Everyone who are having low testosterone donât needs treatment. Those men who have symptoms like fatigue and low libido, they need treatments.
There are several treatments for low testosterone but for younger men, fertility is the most important concept.
Those men who want to be fertile, they should never give a supplemental testosterone because this can turn off sperm production.
Well some other treatments includes weight loss and some lifestyle changes like eating healthier and doing more exercises.
Testosterone replacement therapy options
Some of the testosterone replacement therapy includes:
Injections: The injections are given deep into the muscles which is called as intramuscular injections. These injections can be given every two or three weeks to every three months depending on type of injection.
These injections can be injected by any doctor or nurse and it is not painful if it is carried out properly.
Patches: The patches works almost similar to nicotine patches used for quitting smoke and delivers testosterone through the skin by using a new patch every day.
Testosterone gel: This gel is usually applied to the skin on shoulders, abdomen or in arms. Use it after shower so that it does not gets wash soon.
Testosterone Therapy Risks
What Are The Tests For Testosterone Deficiency
Many older men with testosterone deficiency are never diagnosed. Often the general problems of tiredness, low sex drive and erectile dysfunction are thought to be due to the normal ageing process. Therefore many men don’t go to see a doctor to see whether they have testosterone deficiency.
Testosterone deficiency is often identified if you see your doctor about decreased sex drive or erectile dysfunction. Your doctor will arrange tests, which will include your blood testosterone level.
Men who don’t respond to the medicines that are used to treat erectile dysfunction , should also have their testosterone level checked.
If tests confirm you have low testosterone, further testing can determine if a problem with your testicles or a pituitary gland abnormality is the cause. These further tests may include:
- Testing for other hormone levels .
- Testicular biopsy.
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Testosterone And Cardiovascular Health
In a 2015 advisory, the U.S. Food and Drug Administration warned that testosterone use is possibly associated with increased cardiovascular risk and advised physicians to discuss this risk with patients before initiating testosterone therapy.38 This warning came after two observational studies39,40 and a meta-analysis of randomized controlled trials41 showed an increased cardiovascular risk, and the Testosterone in Older Men with Mobility Limitation randomized controlled trial was stopped early because of concerns about a higher incidence of cardiovascular adverse events in the testosterone treatment group.42 However, other meta-analyses did not find an increased cardiovascular risk,43,44 and several other observational studies have appeared to demonstrate decreased cardiovascular risk with testosterone therapy.4548 Additionally, one of the observational studies that showed increased risk was criticized for its statistical analyses,40 and many of the adverse events leading to the early stoppage of the TOM trial were of questionable clinical significance. Although the findings of the TOM trial are concerning, this study enrolled a high-risk population, and its findings may not be generalizable to most men being considered for testosterone therapy.
What Are The Symptoms Of Low T
- erectile dysfunction, or problems developing or maintaining an erection
- other changes in your erections, such as fewer spontaneous erections
- taking certain prescription medications such as steroids and opiates, especially in excess
Some cases of low T may be linked to other medical conditions, such as:
- hypothalamic or pituitary disease or tumors
- injuries, tumors, or other conditions affecting your testicles including inflammation related to childhood mumps
- inherited diseases, such as Kallmans syndrome, Prader-Willi syndrome, Klinefelter syndrome, or Down syndrome
- diabetes, liver disease, or AIDS
- cancer treatments such as radiation and chemotherapy
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Causes Of Low Testosterone In Young Men
Low testosterone in young men occurs for several reasons that can depend on your health and lifestyle. Many of these causes are manageable if you or a doctor can correctly identify them in order to make certain changes.
Certain physical causes of low T include high blood pressure, cholesterol, and being overweight. Other conditions such as certain diseases and tumors can also be linked to low T. Lifestyle habits like heavy drinking and doing illegal drugs can contribute to low T. In particular, the use of anabolic steroids and other prescription drugs can prevent the body from producing the typical testosterone it needs to function.
A doctor can help diagnosis and potentially identify the underlying causes of low T. First, however, you need to recognize the more common signs of low testosterone in young men.
Most Common Causes Of Low Testosterone
Testosterone levels typically decrease progressively in older men. Testosterone usually peaks in men at 17, remains high until about 40, and then begins to decline, cratering at about 30% of peak levels close to age 70.
Various circumstances, however, may cause boys and men to have low T at much younger ages. Here are some reasons why men under 50 may have testosterone at suboptimal levels below 300 ng/dL:
1. Insufficient Sleep
The majority of the testosterone consumed by the body during the day is replenished at night. Insufficient sleep could lead to depressed testosterone levels.
A study of ten men, restricted to five hours of sleep per night for eight consecutive days, revealed that the subjects demonstrated a 10-15% decrease in testosterone levels, bottoming out in the afternoon or evening. Unsurprisingly, the subjects demonstrated progressively higher levels of fatigue throughout the weekâa symptom, among other things, of low T.
Over time, lack of sufficient sleep leads to elevated levels of the stress hormone cortisol, which correlates with lowered testosterone levels.
Even a person who spends the requisite hours in bed may not be getting sufficient sleep. A common culprit is obstructive sleep apnea , which interrupts the bodyâs respiration during the sleep cycle. Individuals with OSA get less deep sleep and REM sleep over the same period of time as persons who donât have OSA.
2. Excessive Alcohol Consumption
3. Type 2 Diabetes
Treatment For Low Testosterone
Treatment for Low-T will completely depend on the cause of the situation. In some cases, treatment isnt required, and better lifestyle habits must be adopted to solve the issue.
In other situations, your doctor will examine your medical history and, depending on your diagnosis, will suggest a plan to incorporate a mix of lifestyle changes, supplements, and testosterone replacement therapy.
Make sure you do not take any action of your own. Consult an expert in the field, and they will help you move forward in the right direction.
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Many Testosterone Formulations Available
If an otherwise healthy young male presents with low testosterone levels, the underlying cause can be addressed , and testosterone-replacement therapy may be prescribed. However, he should avoid testosterone-replacement therapy if conception is an issue, as it can inhibit sperm production.
The FDA has approved new oral testosterone medications to treat particular conditions that result in hypogonadism, including Klinefelter syndrome or pituitary tumors. These medications are not approved for use in men with low testosterone due to aging. Many other dosage forms of testosterone-replacement therapy are available. For example, testosterone may be given by injection every few weeks or via the skin using a patch, gel, or solution applied every day. Testosterone is also available in tablet form, known as a buccal tablet, that is placed on the front upper gum under the lip and releases over 12 hours. Finally, testosterone-replacement therapy can be administered using implants under the skin that slowly release testosterone over 3 to 6 months.
What Causes Low T In Men Under 30
Low testosterone among young men is not as common as among older men. The causes also tend to be different. Rather than normal aging, low T among men under 30 may be related to high blood pressure or high cholesterol, excessive use of alcohol, illegal drugs, anabolic steroids and some prescription drugs like steroids.
Causes of low T can be categorized as primary or secondary. Primary low T refers to an issue with the testicles, such as an injury, chemotherapy or a developmental problem. Secondary low testosterone occurs when the testicles are normal but the function is compromised due to a problem with the pituitary gland or hypothalamus. This interference can come in many forms, such as obesity, Type 2 diabetes or high blood pressure.
One of the most common causes of low testosterone is obesity. This link between low testosterone and obesity can be found in men of all ages, but it’s perhaps most commonly responsible for younger men. One study found that 40 percent of obese study participants had low testosterone. Fifty percent of obese men with diabetes had low T. Seventy-five percent of men who are considered very obese had low testosterone.
Some injuries and medical conditions are also linked to low T, including pituitary disease, cancer treatment, inherited diseases like Prader-Willi syndrome in which the testicles do not fully descend and injuries or conditions affecting the testicles.
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What Is Male Hypogonadism
Male hypogonadism describes a state of low levels of the male hormone testosterone in men. Testosterone is produced in the testes and is important for the formation of male characteristics such as deepening of the voice, development of facial and pubic hair, and growth of the penis and testes during puberty. Gonadotrophin-releasing hormone, made in the hypothalamus, stimulates the pituitary gland to produce luteinising hormone and follicle stimulating hormone . The gonadotrophins then act on the testes causing them to produce testosterone. Low levels of testosterone can occur due to disease of the testes or from conditions affecting the hypothalamus or pituitary gland. Men can be affected at any age and present with different symptoms depending on the timing of the disease in relation to the start of puberty. In some cases, it can be difficult to tell if there is a true deficiency of testosterone, particularly when the levels are in the borderline range.
How Is Male Hypogonadism Diagnosed
A detailed medical history should be taken. In particular, it is important to find out if virilisation was complete at birth, whether the testes descended and to see if the patient went through puberty at the same time as his peers. The patient should be thoroughly examined and the presence and size of the testes recorded, and whether they are correctly positioned in the scrotum.
Depending on the findings of the above tests, other investigations may be carried out. These include: a bone densitometry test to assess the impact of testosterone deficiency on bone semen analysis genetic studies and an ultrasound of the testes to check for nodules or growths.
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The Zrt Laboratory Blog
Low testosterone in older men, often referred to as male menopause or even andropause is fairly well known and testosterone replacement therapy in this age group has not been without its share of controversy, particularly with respect to heart health. Proper testing and dosing are all-important, as well as understanding a mans physiology and all the factors that affect testosterone levels. For example, when giving testosterone transdermally it is critical to use testing methods such as dried blood spot or saliva to properly assess absorption of testosterone into the body, avoiding the problem of overdosing to achieve normal serum levels.
But while a decline in testosterone is a struggle that older men are coming to expect, what about the alarming suggestion that low testosterone is now becoming more prevalent in younger men? An article published last year has brought some attention to a link between poor health and low testosterone levels in younger men. Lets take a closer look at this article to see who might be at risk.