What Is Genitourinary Syndrome Of Menopause
According to a 2014 article published in the journal Maturitas:
“GSM is defined as a collection of symptoms and signs associated with a decrease in estrogen and other sex steroids involving changes to the labia majora/minora, clitoris, vestibule/introitus, vagina, urethra, and bladder. The syndrome may include but is not limited to genital symptoms of dryness, burning, and irritation; sexual symptoms of lack of lubrication, discomfort or pain, and impaired function; and urinary symptoms of urgency, dysuria and recurrent urinary tract infections.”
Of note, according to the authors of this study, in order for you to be diagnosed as having GSM, your symptoms must be bothersome and unattributable to another etiology or cause. Moreover, many women with GSM may experience some but not all of these symptoms.
Important: How To Use This Information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Estrogen Cream For Vaginal Dryness
The myth that the normal process of aging causes profound physical loss or disability has fueled ageism for eons; a healthy older person has no problem seeing, hearing or thinking. Moreover, many healthy older people still have vigorous libidos and sex lives.
In an estimated 50 percent of women, hormonal changes attributable to menopause can lead to vaginal dryness and other symptoms of genitourinary syndrome of menopause . Despite the availability and efficacy of local vaginal estrogen therapy , only about 60 percent of those experiencing GSM seekor are providedmedical help and guidance. Many women wait a year or more to consult a healthcare provider but the majority will use over-the-counter lubricating gels and creams to alleviate GSM. In other words, a breakdown in the system attributable to both providers and patients keeps several million older women suffering from GSMa condition that is readily treated with estrogen creams and other low-dose vaginal estrogen products.
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Are There Other Things I Can Do To Protect Myself Against Osteoporosis
Doctors have long known that estrogen therapy helps prevent osteoporosis . There are many other ways to protect your bone health. Regular weight-bearing exercise and a diet high in calcium and vitamin D strengthen bones. There are also many bone-building medications available to women today. Your doctor can help you decide the best bone health strategy for you.
Absorbability And Longer Lasting:
Hormones are all fat-soluble because they are derived from cholesterol. ;The inner thigh has a good amount of fat tissue, and it has soft, thin skin compared to other areas of your body. ;This makes it absorb more easily into the skin. Also, because it has a nice fat pad, the release of the hormone will last longer. ;;For example, the inner part of your forearm has thin skin but very little fat. So it will be absorbed quickly, but because of the lack of fat, it will not last long. ;
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What Other Drugs Will Affect Premarin Vaginal Cream
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can interact with conjugated estrogens. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.
How To Curb Estrogen Dominance And Progesterone Deficiency
There are self-help ways to help with estrogen dominance and progesterone deficiency.
For estrogen dominance, non-pharmacological or physiological approaches are important since lifestyle modifications can help menopausal females to lower estrogen levels, naturally and without side effects.
For improving progesterone level progesterone creams are the most popular natural option for reducing the symptoms of progesterone deficiency and estrogen dominance. B6 and limiting dairy in your diet can be helpful as well. For some, dairy can raise prolactin which in turn suppresses ovulation and progesterone.
HRT is also a current trend of help in estrogen dominance and progesterone deficiency but comes with a number of side effects. BHRT is the recommended natural approach by alternative therapy practitioners.
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Our Natural Estrogen Creams With Natural Ingredients And E3 Are Outstanding Products
- Natural Estrogen Cream is a topical estrogen cream, rather than oral supplement, for better effectiveness. Transdermal entering the body through the skin wont interfere with the digestive process of capsules and gel cap pills.
- Estriol is not a dangerous, molecularly changed product. A dose of 2 to 4 mg is the equivalent of .6 to 1.25 mg conjugated estrogen. It has been available in Europe for many years and is now available in the US.
- Bio-identical means that the natural hormone cream is the same as your body would make if it could.
- Bio-availability is highly increased through the application of the skin and even more so when cold processed.
Caution: Please check with your doctor before using, if you are or might be pregnant. Though natural progesterone can be helpful in pregnancy, estriol products are not recommended during pregnancy or lactation.
Precautions Before Using Vaginal Oestrogen
- Do you have breast cancer?
- Are you pregnant or planning a pregnancy?
- Do you get unexplained vaginal bleeding?
- Do you have endometrial hyperplasia?
- Do you have liver disease, asthma, epilepsy, diabetes, or high blood pressure?
- Have you had a heart attack, stroke or blood clot in legs or lungs?
- Do you get migraine headaches?
If so, its important that you tell your doctor or pharmacist before you start using vaginal oestrogen. Sometimes a medicine isnt suitable for a person with certain conditions, or it can only be used with extra care.
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What May Interact With This Medicine
Do not take this medicine with any of the following medications:
- aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
This medicine may also interact with the following medications:
- barbiturates used for inducing sleep or treating seizures
- medicines for fungal infections like ketoconazole and itraconazole
- some antibiotics used to treat infections
- St. John’s Wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Topical Estradiol May Cause Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:
- difficulty falling asleep or staying asleep
- changes in sexual desire
- darkening of the skin on the face
- difficulty wearing contact lenses
- difficulty breathing or swallowing
Topical estradiol may increase your risk of developing cancer of the ovaries and gallbladder disease that may need to be treated with surgery. Talk to your doctor about the risks of using this medication.
Topical estradiol may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .
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How To Use Premarin
If you are taking the extended-release tablets, do not crush, chew, or dissolve them. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
The dosage is based on your medical condition and response to treatment.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day as directed. Follow your dosing schedule carefully. Do not increase your dose or take this medication more often or for a longer time than directed.
Tell your doctor if your condition does not improve or if it worsens.
The Use Of Vaginal Estrogen By Women With A Current Or Prior History Of Breast Cancer
Data do not show an increased risk of cancer recurrence among women currently undergoing treatment for breast cancer or those with a personal history of breast cancer who use vaginal estrogen to relieve urogenital symptoms 16. A nested casecontrol analysis of a cohort study of women with breast cancer who either did or did not use vaginal estrogen showed no increase of recurrence in vaginal estrogen users 17. In another study, the risk of recurrence in women who used vaginal cream was not increased, irrespective of the total dose prescribed 18.
Concerns remain about recurrence risk with use of vaginal estrogen in women with breast cancer who use aromatase inhibitors. Specifically, the threshold for systemic estrogen levels associated with breast cancer recurrence risk has yet to be determined 19. Some authors note that even a small increase in systemic estradiol levels may have a detrimental effect on recurrence risk and that more data are needed before recommendations can be made regarding the use of vaginal estrogen among this population 1620. Typically, aromatase inhibitors decrease circulating estradiol levels from 20 pg/mL to less than 13 pg/mL 2021. Studies have demonstrated an initial increase of serum estradiol with the use of low-dose vaginal estrogen among women taking an aromatase inhibitor, though these levels were not sustained over time and increased cancer recurrence was not noted 11.
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Where Should I Keep My Medicine
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C . Protect from temperatures above 40 degrees C . Do not freeze. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
How To Feel Better In Your Forties
Reduce histamine and mast cell activation to reduce your sensitivity to estrogen.
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Natural Estrogen Replacement: The Great Debate
Because bioidentical estrogen is in the same form as the estrogen in our bodies, some argue that our bodies recognize it easier and therefore it gives us less chance of unwanted side effects.
They contend that bioidentical hormones are clearly superior over synthetic hormones, while others say that there is not enough evidence to prove this.
I recommend talking to your doctor and looking into natural estrogens found in herbal supplements.
Years of women using these herbs with positive experiences along with the low possibility of side effects is a great reason to take natural estrogen supplements.
Your Doctor May Balance The Scales With Progestin
When women who have not had a hysterectomy take supplemental estrogen, they also take a progestin to lower their risk for endometrial cancer. At the moment, it appears that women who use vaginal estrogen cream for a short period of time do not need supplemental progestin. If you are using the product for a long period of time your physician may decide that you need supplemental progestin.
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Where To Apply Bhrt Cream
Bioidentical Hormone Replacement Therapy is very popular and useful for so many people. ;We often prescribe BHRT for the following conditions:
- Menopausal symptoms
This list is not a comprehensive list but gives you an idea of what BHRT can be used for.;Bioidentical hormone applications come in many forms, with transdermal creams being the most common. ;There is a lot of conflicting information on where to apply hormone creams. We recommend to all of our patients to apply hormone cream to the inner thigh.;
Whether you are using progesterone cream, estradiol, estriol, biest, testosterone, or DHEA creams, the inner thigh is typically the best place to apply the cream. Whether you are male or female, the inner thigh is the proper location to apply your cream. You can also apply BHRT cream to the back of the knee, which I will further explain. ;;
Choosing The Best Type Of Estrogen Therapy
When deciding what type of estrogen therapy to get, work closely with your doctor. While oral estrogen has been around for a long time and is well studied, some modes of taking hormone therapy are not. They may have lower risks or different risks that we don’t know about yet. Your doctor should be up to date on the latest research.
Right now, the full risks of hormone therapy are unclear. So if you do decide to get ERT, experts generally recommend that you get it at the lowest dose for the shortest time possible. Talk to your doctor about how long you should expect to take ERT and how you can limit your risks.
ACP Medicine web site: “Menopause.”
Canonico M et al, Circulation, Feb. 20, 2007; vol 115: pp 840-845.
MedicineNet web site: “Hormone Creams: Safe and Effective?”
National Cancer Institute web site: “How to Deal with Surgical Menopause.”
National Institutes of Health web site: “Facts About Menopausal Hormone Therapy.”
National Institutes of Health Medline Plus web site: “Estrogen,” “Estrogen Vaginal,” “Estradiol Topical,” “Estradiol Transdermal.”
National Women’s Health information Center: “Menopause and Menopause Treatments.” WebMD Medical Reference: “Estrogen Replacement Therapy,” “Low Dose Estrogen for Dryness and Atrophy.”
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What Estrogen Does In Your 40s
Night sweats, mood swings, and crazy heavy periods. Is this menopause already? And youre only 42? No, menopause could still be a decade away. This is perimenopause or second puberty, which is the two to twelve years before your final period.
Perimenopause is different from menopause, which is the life phase that begins one year after your final period.
Perimenopausal symptoms are temporary and respond to simple treatments provided below.
The first step to feeling better in your forties is to understand whats happening with your body. Put simply, during perimenopause, estrogen goes on a roller coaster ride while progesterone quietly leaves the scene.
To Use Estradiol Emulsion Follow These Steps:
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
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Who Should Not Take Vaginal Estradiol
Do not use vaginal estradiol if you have:
- Undiagnosed abnormal genital bleeding
- Known, suspected or history of breast cancer
- Known or suspected estrogen-dependent neoplasia
- Active deep vein thrombosis
- Pulmonary embolism
- A history of deep vein thrombosis, pulmonary embolism, active arterial thromboembolic disease , or a history of these conditions
- Known anaphylactic reaction or angioedema (severe allergic reaction to estradiol
- Liver dysfunction or disease
Premarin Vaginal Side Effects
Get emergency medical help if you have signs of an allergic reaction to Premarin Vaginal: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
signs of a blood clot – sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;
swelling or tenderness in your stomach;
memory problems, confusion, unusual behavior;
unusual vaginal bleeding, pelvic pain;
a lump in your breast; or
high levels of calcium in your blood – nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, lack of energy.
Common Premarin Vaginal side effects may include:
breast pain; or
vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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