Conditions Treated By Estriol And Estradiol
Estrogen is most commonly used as hormone replacement therapy for women experiencing symptoms of menopause. Estrogens are often combined with progesterone or other steroid hormones called progestins. Estradiol is FDA approved to treat symptoms of menopause. These symptoms include vasomotor symptoms such as hot flashes, night sweats, and flushing of the skin. Other menopausal symptoms include vaginal atrophy, or vaginal dryness, inflammation, and thinning.
Estradiol can also be used in late-stage breast cancer that has spread to other parts of the body. It is used to help decrease the severity of the cancer . For women with ER-positive breast cancer that has metastasized, high dose estradiol may be used as therapy. According to studies from Maturitas, if breast tumors express the ESR1 gene, the cancer may respond well to estradiol therapy.
Estradiol tablets are also approved to treat advanced prostate cancer that is androgen dependent. While estrogen levels can contribute to prostate cancer, estradiol can be used as palliative treatment in some men. Studies show that estradiol is an effective form of therapy for certain types of prostate cancer.
How Is Low Estrogen Treated
Women who have low levels of estrogen may benefit from hormonal treatment. Hormonal treatment is the standard for low estrogen. There are non-hormonal options to help relieve symptoms. Non-hormonal options are preferred for women at high risk for breast cancer, blood clots, stroke, or liver disease.
What Other Drugs Will Affect Prempro
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can interact with conjugated estrogens and medroxyprogesterone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.
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What Are The Pros And Cons Of Using Over
When considering over-the-counter estrogen cream to help relieve the symptoms of menopause, it is important to look at both the pros and cons. On the positive side, these creams are readily available and do not require a doctors prescription. There is also some evidence that they can help reduce problems like hot flashes and vaginal dryness. Unfortunately, their production is not well regulated, which means that the amount of estrogen in one cream may be very different from the amount in another, and there may even be differences between batches of the same brand. Using these creams may also carry some of the same health risks as using prescription creams, and do not have the benefit of a doctors supervision.
One of the main benefits of over-the-counter estrogen cream is its availability. Women suffering from menopausal symptoms can easily purchase it without having to wait to see their doctor. They may be able to use it to find quick relief if symptoms become extremely uncomfortable and they have no other options.
Why It Is Essential To Maintain The Level Of Testosterone In Your Body
It is well known that testosterone is the sex hormone that helps in the sex drive of a man and in producing sperm cells. It plays a significant part in the improvement of masculinity in a man by increasing his muscle mass, facial hair and all-round physique. Testosterone also helps in controlling the mood, energy, sleep and also the distribution of fat. With lowered levels of testosterone, men can suffer significant damages like low sex drive, fatigue, infertility, depression and even insomnia.
While in women, they can experience issues such as male pattern baldness, facial hair growth, infertility and acne. Some men lack essential nutrients like zinc, magnesium and vitamin D, and these are essential nutrients which assist in producing testosterone they are in fact, the main ingredients. With an effective workout and a fatty diet, testosterone can also be enhanced coupled with over the counter testosterone boosters.
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Side Effects Of Estriol And Estradiol
The most common side effects of estrogen therapy include menstrual changes , spotting, pain during periods , breast tenderness, nausea, vomiting, and headache. Other side effects of topical and oral estrogens include bloating, weight gain, and hair loss.
Topical estriol or estradiol may cause more direct effects when applied to the vagina. Side effects can include itching and increased secretions. Other more serious side effects may include fungal infections .
Estrogen has been shown to alter or increase the production of melanin, a substance responsible for the skins pigment. Estrogen can increase pigment and darken the skin in some cases.
Severe side effects of estrogen use include high blood pressure , heart attack, blood clots , worsening of asthma, gallbladder disease, and low calcium levels. Other severe adverse effects can include the enlargement of fibroids in the uterus as well as the increased risk of breast and cervical cancer.
Information On Estrogen Hormone Therapy
Overview of Feminizing Hormone TherapyUCSF Transgender CareUniversity of California – San FranciscoJuly, 2020
Hi, I’m Dr. Maddie Deutsch, Associate Professor of Clinical Family & Community Medicine at the University of California San Francisco , and Medical Director for UCSF Transgender Care. In this document I will review various aspects of feminizing hormone theray, including, choices, risks, and unknowns associated with feminizing hormone therapy.
As you prepare to begin treatment, now is a great time to think through what your goals are. Do you want to get started right away on a path to the maximum degree of medically appropriate feminizing effects? Or, do you want to begin at a lower dose and allow things to progress more slowly? Perhaps you are seeking less-than-maximal effects and would like to remain on a low dose for the long term. Thinking about your goals will help you communicate more effectively with your medical provider as you work together to map out your care plan.
Many people are eager for hormonal changes to take place rapidly which is totally understandable. It is important to remember that the extent of, and rate at which your changes take place, depend on many factors. These factors primarily include your genetics and the age at which you start taking hormones.
There are four areas where you can expect changes to occur as your hormone therapy progresses. Physical, emotional, sexual, and reproductive.
The first is physical.
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Is It Time For Me To Try Hormone Therapy
Several factors play into whether hormone replacement therapy is the best option for you. Your age is one factor. Your doctor will also want to consider whether youâve had a hysterectomy and whether you have certain health risks, such as a family or personal history of breast cancer or clotting disorders.
A Survivor’s Guide To Surgical Menopause
Because surgical menopause is different from natural menopause, women who are in surgical menopause can benefit from the latest research and strategies for maximizing health. Whether you want to supplement your hormones through HRT or whether you choose a different approach, it helps to understand how this affects your body.
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Why Does Your Estrogen Level Matter
Estrogen is a hormone. Although present in the body in small amounts, hormones have big roles in maintaining your health.
Estrogen is commonly associated with the female body. Men also produce estrogen, but women produce it in higher levels.
The hormone estrogen:
- is responsible for the sexual development of girls when they reach puberty
- controls the growth of the uterine lining during the menstrual cycle and at the beginning of a pregnancy
- causes breast changes in teenagers and women who are pregnant
- is involved in bone and cholesterol metabolism
- regulates food intake, body weight, glucose metabolism, and insulin sensitivity
Girls who havent reached puberty and women approaching menopause are most likely to experience low estrogen. Still, women of all ages can develop low estrogen.
Common symptoms of low estrogen include:
Natural Progesterone Vs Progestin
Let me be crystal clear here, progestin, the synthetic stuff you find in hormonal birth control like the combination pill and IUDs is absolutely nothing like your natural progesterone. And I take issue with this misinformation being spread.
You know how many times I come across a research study saying progesterone does harm only to find they were studying progestin? Or how about how the fact that the pharmacist hands out warnings about progestins when I prescribe bioidentical progesterone to my patient, which leaves them scared and confused? And believe me, the progestin outcomes are scary.
Its this kind of misinformation that confuses women and keeps them from getting the help they need.
Progestin is altered in order to create a patent and may be synthesized from androgens . On a biochemical level, it looks nothing like the natural stuff you make. And progestin brings a whole lot of inconvenient and downright scary side effects like increased cancer risk, heart attack and mood disorders.
Estrogen Side Effects And Risks
Hormone therapy is not without its risks. In fact, hormone therapy is not used as widely as it once was because research began revealing complications with long-term use, such as cancer and heart risks.
However, thanks to these studies, doctors and medical researchers have a better understanding of who will benefit most from estrogen therapy and who should try other treatments.
The risk factors and side effects associated with estrogen use include:
- Blood clots: Estrogen increases your risk of blood clots, which can cause stroke, heart attack, and even death.
- Cancer: Estrogen may increase your risk of certain cancers, specifically breast cancer. Talk with your doctor about your personal health history, your family history, and your risk of breast cancer.
- Birth defects: If youre using estrogen or hormone therapy and become pregnant, your pregnancy may end prematurely. If youre able to carry a pregnancy to full term, birth defects are common for babies born to women using estrogen.
- Dense breast tissue: Women who take estrogen may develop dense breast tissue. Dense tissue makes reading mammograms harder, so detecting breast cancer in its early stages may be difficult.
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How To Use Estrace
If you are taking the extended-release tablets, do not crush, chew, or dissolve them. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
The dosage is based on your medical condition and response to treatment.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day as directed. Follow your dosing schedule carefully. Do not increase your dose or take this medication more often or for a longer time than directed.
Tell your doctor if your condition does not improve or if it worsens.
Important Questions To Ask About Menopause Hormone Medicines
- Are hormones right for me? Why?
- What are the benefits?
- What are the serious risks and common side effects?
- How long should I use hormone therapy?
- What is the lowest dose that will work for me?
- Are there any non-hormone medicines that I can take?
Want more information about menopause? Check the FDA website at: www.fda.gov/menopause
The drug and risk information in this booklet may change. Check for the latest facts on each product listed in this booklet.
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What Else Can I Do To Ease Menopause Symptoms
There are many things you can do to curb hot flashes, night sweats, insomnia, vaginal dryness, and lost libido. Lifestyle changes — such as regular exercise, a healthy diet, relaxation techniques, and keeping a regular sleep schedule — can help. If you smoke, quit . Avoid caffeine and alcohol. Lubricants can greatly ease vaginal dryness and heighten sexual sensation.Stay active to avoid depression and seek social support from woemn like you
Your doctor can give you more information about these techniques and other treatment options. The use of selective serotonin reuptake inhibitors has become more common in women who are not good candidates for hormone therapy or prefer not to use hormones. Paroxetine is the only non hormonal therapy specifically approved by the FDA for hot flahes, but some relief has been found with gabapentin .
What Are The Main Differences Between Estriol And Estradiol
Estriol is sometimes referred to as E3 or oestriol. It is the weakest form of estrogen in the body. Like estrone, estriol levels naturally increase during pregnancy. Estriol is FDA approved for urinary incontinence in female dogs after removal of the ovaries and uterus. Estriol is not FDA-approved as a prescription drug for humans. However, some compounding pharmacies may sell estriol compounded with other drugs.
Estradiol , or E2, is the most potent of the three estrogens. Some forms of estradiol can be found in low-dose birth control pills for premenopausal women. It is primarily used as a tablet, patch, or cream for estrogen replacement therapy. Estradiol can be found in FDA-approved products such as Estrace, Vivelle-Dot, Vagifem, and Climara, among others. The FDA has also approved estradiol in bioidentical hormone therapy with progesterone.
|Main differences between estriol and estradiol|
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What Other Information Should I Know
Keep all appointments with your doctor and the laboratory. You should have a complete physical exam, including blood pressure measurements, breast and pelvic exams, and a Pap test at least yearly. Follow your doctor’s directions for examining your breasts report any lumps immediately.
If you are taking hormone replacement therapy to treat symptoms of menopause, your doctor will check every 3 to 6 months to see if you still need this medication. If you are taking this medication to prevent thinning of the bones , you will take it for a longer period of time.
Before you have any laboratory tests, tell the laboratory personnel that you take hormone replacement therapy, because this medication may interfere with some laboratory tests.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
What Is Male Breast Enlargement
The most common reason why men are interested in male breast enlargement is that they are either cross-dressers or transgender, hoping to have a more realistic bust line in their clothing. Many of these men do not wish to undergo hormonal treatments that can cause weight gain and muscle loss, so they opt for natural male breast enlargement products that are easier on the body yet equally as effective.
Even though you may think that men could never have natural breasts, that is simply not the case. By altering a mans natural hormonal balance, a man will begin to grow breasts just like a woman would. Products that can help a man achieve this will usually not alter any other aspect of his body, which is also very important.
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Proper Use Of Estrogen And Progestin Combination
Estrogens and progestins usually come with patient information or directions. Read them carefully before taking estrogen and progestin combination .
Take estrogen and progestin combination only as directed by your doctor. Do not take more of it and do not take or use it for a longer time than your doctor ordered. Try to take the medicine at the same time each day to reduce the possibility of side effects and to allow it to work better.
For patients taking estrogens and progestins by mouth:
- Nausea may occur during the first few weeks after you start taking estrogens. This effect usually disappears with continued use. If the nausea is bothersome, it can usually be prevented or reduced by taking each dose with food or immediately after food.