What Does Estrogen Cream Do

S For Taking Estrogen

Estrogen can be taken in a number of different ways. People receive estrogen through a pill, injection, patch, or even a topical cream. It’s not just a matter of preference. The route by which people take estrogen affects some of the risks of estrogen treatmentestrogen is absorbed by the body differently depending on how you take it.

Much of the research on the risks of estrogen treatment focus on oral estrogensthose taken by mouth. What research has found is that oral estrogen seems to cause an increased risk of a number of problematic side effects when compared to topical or injected estrogens. This is because of the effects of ingested estrogen on the liver when it passes through that organ during the process of digestion.

This is referred to as the hepatic first pass effect and it is not an issue for estrogen treatment that isn’t taken in pill form. The hepatic first pass effect causes changes in a number of physiological markers that affect cardiovascular health.

These changes may lead to an increase in blood clotting and reduced cardiovascular health. They are not seen as often, if at all, with non-oral estrogens. Therefore, non-oral estrogens may be a safer option.

Estrogen Applied Topically And Benefits For Skin

At the urging of Arandjel, I decided to take a look at estrogen as an anti-aging skin care ingredient. Im confining my research to topical estrogen and what its positive effects if any — might be. For those interested in the broader topic of hormone replacement therapies, theres a discussion thread led by Susan after my post on the Second Half of Your Life. Here I want to try to work out if the good imparted by topical estrogen outweighs the possible risks.

Why Is This Medication Prescribed

Estradiol topical gel and emulsion are used to treat and prevent hot flushes in women who are experiencing menopause . Estradiol topical gel is also used to treat vaginal dryness, itching, and burning in women who are experiencing menopause. However, women whose only bothersome symptoms are vaginal burning, itching, and dryness may benefit more from a medication that is applied topically to the vagina. Estradiol is in a class of medications called estrogen hormones. It works by replacing estrogen that is normally produced by the body.

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What Are The Main Differences Between Estrace And Premarin

Estrace is available in brand and generic form and contains the ingredient estradiol. Estrace is available as a vaginal estrogen cream, and also as an oral tablet.

Premarin is available as a brand-name drug only. It contains conjugated estrogens, purified from pregnant mares urine . Premarin is available as a vaginal estrogen cream, oral tablet, or injection.

Get Help With Estrogen Balance With Dr Randolph

If youre suffering from the side effects that result from low estrogen, we can help. At Dr. Randolphs Ageless Wellness Center, we have decades of experience in hormone replacement therapy and offer a wide range of products services designed to help you reach and maintain hormone balance. Bi-Est, our newest estrogen cream, is specifically formulated to offer the best 80/20 balance of estriol and estradiol that maximizes the health benefits of estrogen.

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What Are The Advantages And Disadvantages Of Estrogen Cream For Treatment Of Atrophic Vaginitis

The advantages of vaginal estrogen cream include lower plasma levels and greater effectiveness than with oral treatment. Disadvantages include compliance issues due to the application process itself and its messiness; as a result, the silastic vaginal ring and vaginal tablets were developed.

A randomized, multicenter, double-blind study by Kroll et al that included 550 sexually active postmenopausal women with moderate-severe dyspareunia reported that lower-dose estradiol vaginal cream dosed three applications/week reduced the level of dyspareunia, decreased vaginal pH, and improved vaginal cytology when compared to the placebo.

What Happens To Estrogen During Menopause

During perimenopause , estrogen levels change at an irregular rate. Sometimes there is even more estrogen present in the body than during the childbearing years. This constant ebb and flow of estrogen can cause several uncomfortable symptoms, such as vaginal dryness, hot flashes, night sweats, low libido, and low energy.

During menopause, postmenopause stages of a womans life, estrogen levels are very low. The body is no longer producing estrogen through the ovaries and therefore many women may experience problems such as:

• Painful sex due to a lack of vaginal lubrication
• An increase in urinary tract infections due to a thinning of the urethra
• Mood swings
• Headaches or accentuation of pre-existing migraines
• Depression
• Fatigue

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Vaginal Estrogen And Sexual Function

It is well established that estrogen deficiency occurring at and beyond menopause may disrupt many of the physiological responses which characterize sexual arousal, including smooth muscle relaxation, vasocongestion and vaginal lubrication. The decreased lubrication and tissue elasticity in addition to shortening of the vaginal vault can cause dyspareunia. In addition, decreased sensory response and patient reaction to her social situation, loss of a long-term partner, changes in body image, and medication may cause undesired alterations in sexual habits. Other factors which may contribute to decreased sexual function include length of relationships, aging, physical and mental health problems, loss of partners health, medication use, and other financial and social stressors. The intent of this section is to address only those changes that may be affected by use of various forms of vaginal estrogen administration.

Bachmann, and others , noted that restoring vaginal epithelial health with estrogen results in increased vaginal compliance,decreased vaginal pH, increased vaginal blood flow and lubrication. Changes in vaginal fluids and electrolytes have been noted with one month of therapy and in pH, blood flow and vaginal electropotential in 18-24 months. Women subsequently report decreased vaginal irritation, pain, dryness and burning during intercourse,, which may lead to increased sexual desire, arousal , and improved quality of life.

Treatment And Gender Surgery

Currently, most surgeons recommend that transgender women and transfeminine people stop taking estrogen before they undergo gender affirmation surgery. This is because of the potentially increased risk for blood clots that is caused both by estrogen and by being inactive after surgery. However, it is unclear whether this recommendation is necessary for everyone.

Transgender women and non-binary feminine people who are considering surgery should discuss the risks and benefits of discontinuing their estrogen treatment with their surgeon. For some, discontinuing estrogen is no big deal. For others, it can be extremely stressful and cause an increase in dysphoria. For such people, surgical concerns about blood clotting may be manageable using postoperative thromboprophylaxis.

However, individual risks depend on a number of factors including the type of estrogen, smoking status, type of surgery, and other health concerns. It is important that this be a collaborative conversation with a doctor. For some, discontinuing estrogen treatment may be unavoidable. For others, risks may be managed in other ways.

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What Is Vaginal Oestrogen

Vaginal oestrogen;is available as a cream or as pessaries that are inserted into the vagina. It;is used to;ease vaginal;symptoms of menopause;such as;vaginal dryness, burning or itching.Vaginal;oestrogen;may also be used to treat the vaginal tissues before and after;vaginal surgery.;Since vaginal;oestrogen;is applied directly into the vagina,;less is absorbed into the body, reducing the chance of side effects.In New Zealand,;vaginal;oestrogen;is called Ovestin cream® and;Ovestin pessaries®.

Answer: Estrogen Cream For Increasing Size

No OTC medicine increases breast size in Men ! Stay away from supplements that claim that they can do this- it is a scam. If it worked it would have been tested and FDA approved for this usage. The only medicine that might work would be for male breast enlargement caused by an endocrine disorder. You would need to see an endocrinologist for a work up if this involves you.;

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What Should I Avoid While Using Estrogel

Avoid getting Estrogel gel in your eyes. If this does happen, rinse with water.

Wait at least 25 minutes after applying Estrogel before you apply sunscreen to the same skin area.

Grapefruit and grapefruit juice may interact with estradiol and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

What Form Does This Medication Come In

Each;g of white, vaginal cream contains 0.625;mg of conjugated estrogens CSD.;Nonmedicinal ingredients:;cetyl alcohol, cetyl esters wax, glycerin, glyceryl monostearate, methyl stearate, mineral oil, phenylethyl alcohol, propyl glycol monostearate, sodium lauryl sulfate, water purified, and white wax. Gluten-, paraben-, sugar-, sulfite-, and tartrazine-free.

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Different Types Of Vaginal Estrogen Creams

Vaginal estrogen creams are available in different types. There is the natural kind, which is made from plant or human estrogen to tighten vagina skin. This type is the most commonly used and has even managed to replace the earlier types used before. The natural kind of product have fewer side effects and are therefore more preferred. There are some types of these products that are only available with a prescription. These are the specially made gels that you can only find more about them from your physician. There is another type that is easily available over the counter, but it is wise to seek the recommendation of your physician before using any of them. There are the phytoestrogen creams that help in eradicating skin problems. There are some conjugated types that are used to treat post menopause changes.

To Use Estradiol Gel Follow These Steps:

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Where Should I Keep My Medicine

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C . Protect from temperatures above 40 degrees C . Do not freeze. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What Other Drugs Will Affect Premarin Vaginal Cream

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can interact with conjugated estrogens. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.

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Less Serious But Common Side Effects Include:

• Headache
• Irregular vaginal bleeding or spotting
• Stomach or abdominal cramps or bloating
• Nausea and vomiting
• Vaginal yeast infection
• Reactions from inserting Premarin Vaginal Cream, such as vaginal burning, irritation, and itching

Donât use Premarin Vaginal Cream if youâve had unusual bleeding, breast or uterine cancer, blood clots, liver problems, stroke or heart attack, are allergic to any of its ingredients, or think youâre pregnant.

These are not all the possible side effects of Premarin Vaginal Cream. For more information, ask your healthcare provider or pharmacist for advice about side effects.

What Is Estriol Used For

If you would like to read more about Estrogen Dominance, check out our blog: What Does Estrogen Dominance Feel Like?. Estrone stimulates the estrogen receptor moderately, while estradiol has a very strong effect on the receptor. ;Estriol, like the other estrogens, stimulates estrogen receptors. But it does so more weakly than estrone and estradiol. For example, imagine a door is the estrogen receptor. Estrone will approach the door and knock firmly on the door to get someone inside to open it. ;

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Important: How To Use This Information

This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Bladder Storage Symptoms And Urinary Incontinence

The decrease in ovarian estrogen production at the time of menopause causes atrophic changes in the vulvar, vaginal, urethral and bladder tissue. While vasomotor symptoms may resolve in a few months or years, vaginal and other urogenital symptoms may actually increase as the patient ages. The effects of estrogen are manifest by the presence of Estrogen Receptors . Estrogen receptors have been shown in biopsy specimens from the bladder trigone, proximal urethra, distal urethra, vagina and vesico-vaginal connective tissue contiguous with the bladder neck., , While ERs were present in urethral squamous epithelium, they were not present in urothelial tissue of the lower urinary tract. Progesterone receptors are more variable and found mostly in subepithelial tissues.

Decreased estrogen levels after menopause causes atrophic urogenital symptoms with several recent studies confirming resultant dysuria and other lower urinary tract symptoms such as urgency and frequency. Iosif studied a cohort of Swedish women and found a 50% incidence of urogenital symptoms including dryness, itching, burning, urgency and frequency. Barlow reported that 23-40% of menopausal women report at least one urogenital symptom. In a 1954 paper, Youngblood reported that symptoms of urgency and irritation were due to atrophic urethritis which is defined at symptoms of UTI without a positive culture.

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Whi Changed Menopause Treatment

In 2002, the Women’s Health Initiative study was abruptly halted because it was found that estrogen/progestin tablets were actually increasing the risk of heart attack, stroke, dementia and breast cancer for women enrolled in the study. Since that time, experts have recommended that physicians prescribe the lowest possible dose of estrogen for the shortest possible amount of time. Vaginal estrogen creams, if used correctly, can fill this need. They are also more effective for women who have vaginal menopausal symptoms like dryness, burning or itching but don’t have hot flashes and other problems associated with menopause.

When You Must Not Use It

Do not use Ovestin Cream if:

• you have or have ever had breast cancer, or if you are suspected of having it.
• you are pregnant or think you may be pregnant
• you have or if it is suspected that you have cancer which is sensitive to oestrogens, such as cancer of the lining of the womb
• you have any unexplained vaginal bleeding, which has not been evaluated by your doctor
• you have excessive thickening of the lining of your womb that is not being treated
• you have or have had a blood clot or the lungs )
• you have a blood clotting disorder
• you have or have had a disease caused by blood clots in the arteries such a heart attack, stroke or angina
• you have or ever have had a liver disease and your liver function tests have not returned to normal
• you have had an allergic reaction to estriol, or any of the other ingredients of Ovestin
• you have a rare blood problem called porphyria .

Do not use Ovestin Cream if you have an allergy to:

• any medicine containing estriol
• any of the ingredients listed at the end of this leaflet.

Some of the symptoms of an allergic reaction may include:

• shortness of breath
• swelling of the face, lips, tongue or other parts of the body
• rash, itching or hives on the skin.

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Take Special Care With Ovestin Cream

As well as benefits, Ovestin has some risks which you need to consider when you are deciding to start or continue treatment.

Medical check-upsBefore you start using Ovestin Cream, your doctor should ask about your own and your family’s medical history. Your doctor may decide to examine your breasts and/or your abdomen, and may do an internal examination. You will also have periodic check-ups, especially examinations of the breasts. Your doctor will tell you how often these tests should be performed.

Once you have started using Ovestin Cream, you should see your doctor for regular check-ups . At these check-ups, your doctor may discuss with you the benefits and risks of continuing to use Ovestin.

Certain conditions may be made worse by hormone replacement therapy . If you have or have had any of the following conditions and/or which were worse during pregnancy or with previous use of hormones tell your doctor who will monitor you closely:

• uterine fibroids
• endometriosis
• clots in the blood vessels or an increased risk of developing this
• if anyone in your family has ever had an oestrogen-dependent cancer, such as a close relative who has had breast cancer or cancer of the lining of the womb
• high blood pressure
• systemic lupus erythematosus
• endometrial hyperplasia
• epilepsy

Tell your doctor if you notice any change in your condition while using Ovestin.

Reasons for immediately stopping Ovestin Cream: